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MIRAGE
phospholipase C delta 3

Summary
Gene Symbol
  • PLCD3
Organism
Macaca mulatta (Rhesus monkey)
NCBI Gene
715924
KEGG Gene ID
mcc:715924
PubChem
715924
Annotation
Keyword
  • Calcium
  • Hydrolase
  • Lipid degradation
  • Metal-binding
  • Reference proteome
  • Transducer
Proteins
Displaying 1 entry
UniProt Protein Name
F7GU82
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
Functional Category
  • E: Amino acid transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 5 entries
Gene Ontology
hydrolase activity
lipid metabolic process
phosphatidylinositol phospholipase C activity
phosphatidylinositol-mediated signaling
release of sequestered calcium ion into cytosol
Displaying all 7 entries
InterPro
C2 domain superfamily
C2 domain
EF-hand domain pair
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Phosphatidylinositol-specific phospholipase C, X domain
Phosphoinositide phospholipase C family
Phospholipase C, phosphatidylinositol-specific, Y domain
KEGG BRITE Database
Orthology
K05857
Name
phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
References
Rhea

RHEA:33179

H2O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)
H+ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP014610
Gene Name
phospholipase C, delta 3
Ortholog
Displaying entries 11 - 20 of 84 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
100352032 RABIT07820
100395085 CALJA35460
100443819 PONAB13154
100521111 PIGXX02123
100604799 NOMLE15571
100695378 ORENI54376
100724912 CAVPO18989
100759620 CRIGR12870
100916816 SARHA01452
100958789 OTOGA14920
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025