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MIRAGE
thyroid peroxidase
Summary
- Gene Symbol
-
- TPO
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Congenital hypothyroidism
- Disease variant
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Heme
- Hydrogen peroxide
- Proteomics identification
- Reference proteome
- Signal
- Sushi
- Thyroid hormones biosynthesis
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| thyroid hormone generation |
|
|
| response to oxidative stress |
|
|
| embryonic hemopoiesis |
|
|
| hormone biosynthetic process |
|
|
| hydrogen peroxide catabolic process |
|
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular region |
|
|
| obsolete extracellular space |
|
|
| plasma membrane |
|
|
| cell surface |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| iodide peroxidase activity |
|
|
| peroxidase activity |
|
|
| peroxidase activity |
|
|
| peroxidase activity |
|
|
| calcium ion binding |
|
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2921 | glomerulonephritis | |
| DOID:0112186 | thyroid dyshormonogenesis 2A | |
| DOID:0050328 | congenital hypothyroidism |
