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CCR4-NOT transcription complex, subunit 2

Summary

Gene Symbol

Cnot2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

72068

KEGG Gene ID

PubChem

72068

Alliance of Genome Resources

MGI:1919318

Annotation

Keyword

Alternative splicing
Cytoplasm
Developmental protein
Nucleus
Phosphoprotein
Proteomics identification
RNA-mediated gene silencing
Reference proteome
Repressor
Transcription regulation
Translation regulation

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A0A1S6GWJ6	CCR4-associated factor 2
Q5CZY5	CCR4-associated factor 2
H7BWX6
Q8C5L3	CCR4-associated factor 2
E9Q027	CCR4-associated factor 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	ISS
negative regulation of transcription by RNA polymerase II	ISO
negative regulation of transcription by RNA polymerase II	IEA
nuclear-transcribed mRNA poly(A) tail shortening	IBA
trophectodermal cell differentiation	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

cellular developmental process [inference]

cell differentiation [inference]

trophectodermal cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

trophectodermal cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of developmental process [inference]

regulation of stem cell population maintenance

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of translation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of translation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

regulation of organelle assembly [inference]

regulation of cytoplasmic mRNA processing body assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nuclear-transcribed mRNA poly(A) tail shortening

regulatory ncRNA-mediated gene silencing

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

regulation of organelle assembly [inference]

regulation of cytoplasmic mRNA processing body assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

regulation of multicellular organismal process [inference]

regulation of stem cell population maintenance

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA
cytosol	ISO
cytosol	TAS
plasma membrane	ISO
CCR4-NOT complex	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
transcription corepressor binding	ISS
transcription corepressor binding	ISO
transcription corepressor binding	IEA
poly(A)-specific ribonuclease activity	ISS
poly(A)-specific ribonuclease activity	ISO