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MIRAGE
transient receptor potential cation channel subfamily C member 6
Summary
- Gene Symbol
-
- TRPC6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- Alternative splicing
- Calcium channel
- Cell membrane
- Disease variant
- Glycoprotein
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Y210 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation transport |
|
|
| positive regulation of cytosolic calcium ion concentration |
|
|
| single fertilization |
|
|
| neuron differentiation |
|
|
| positive regulation of ion transmembrane transporter activity |
|
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| membrane |
|
|
| membrane |
|
|
| cation channel complex |
|
|
| slit diaphragm |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding |
|
|
| ion channel activity |
|
|
| monoatomic ion channel activity |
|
|
| monoatomic cation channel activity |
|
|
| calcium channel activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Short transient receptor potential channel
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1312 | focal segmental glomerulosclerosis | |
| DOID:0111129 | focal segmental glomerulosclerosis 2 | |
| DOID:8544 | chronic fatigue syndrome | |
| DOID:0080379 | nephrotic syndrome type 2 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 22068 | MGI:109523 |
