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translin

Summary

Gene Symbol

TSN

Organism

Homo sapiens (human)

External Links

NCBI Gene

7247

KEGG Gene ID

PubChem

7247

Alliance of Genome Resources

HGNC:12379

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
DNA-binding
Endonuclease
Magnesium
Metal-binding
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KRM8	Component 3 of promoter of RISC
Q15631	Component 3 of promoter of RISC

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
RNA metabolic process	IEA
siRNA processing	IDA
post-transcriptional gene silencing by RNA	NAS
regulatory ncRNA-mediated post-transcriptional gene silencing	NAS

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing [inference]

regulatory ncRNA processing [inference]

siRNA processing

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
male germ cell nucleus
nucleus	EXP
nucleus	TAS
nucleus	IBA
nucleus	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

endonuclease complex [inference]

endoribonuclease complex

catalytic complex [inference]

endonuclease complex [inference]

endoribonuclease complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

endoplasmic reticulum

Displaying entries **1 - 5** of 12 in total

1

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3

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Last »
GO Term	Evidence Code	PMID
nucleic acid binding	IEA
DNA binding	TAS
single-stranded DNA binding	IEA
RNA binding	IBA
RNA binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

catalytic activity, acting on a nucleic acid [inference]

nuclease activity [inference]

endonuclease activity

mRNA binding

protein binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

translin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
RNA metabolic process
sequence-specific DNA binding

Displaying **all 5** entries
InterPro
Translin family
Translin superfamily
Translin, C-terminal
Translin, N-terminal
Translin

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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Acknowledgements