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phospholipase C, epsilon 1

Summary

Gene Symbol

Plce1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74055

KEGG Gene ID

PubChem

74055

Annotation

Keyword

Calcium
Cell membrane
Cell projection
Cytoplasm
Golgi apparatus
Guanine-nucleotide releasing factor
Hydrolase
Lipid degradation
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Transducer

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K4S1	Phosphoinositide phospholipase C-epsilon-1 Phospholipase C-epsilon-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 30 in total

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GO Term	Evidence Code	PMID
lipid metabolic process	IEA
diacylglycerol biosynthetic process	ISS
diacylglycerol biosynthetic process	ISO
diacylglycerol biosynthetic process	IEA
signal transduction	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

intracellular signal transduction

phosphatidylinositol-mediated signaling

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction

Ras protein signal transduction

metabolic process [inference]

phosphorus metabolic process [inference]

phosphatidylinositol metabolic process

catabolic process [inference]

lipid catabolic process

biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

primary metabolic process [inference]

lipid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

lipid catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

intercellular transport [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

developmental process [inference]

anatomical structure development [inference]

glomerulus development

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

intercellular transport [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium assembly

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

G protein-coupled receptor signaling pathway

phospholipase C-activating G protein-coupled receptor signaling pathway

intracellular signal transduction

phosphatidylinositol-mediated signaling

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction

Ras protein signal transduction

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of lamellipodium assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

regulation of lamellipodium organization [inference]

regulation of lamellipodium assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of lamellipodium assembly

positive regulation of lamellipodium organization [inference]

positive regulation of lamellipodium assembly

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
Golgi membrane	ISS
Golgi membrane	IEA
cytosol	ISS
cytosol	ISO
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
phosphatidylinositol-4,5-bisphosphate phospholipase C activity	ISS
phosphatidylinositol-4,5-bisphosphate phospholipase C activity	ISO
phosphatidylinositol-4,5-bisphosphate phospholipase C activity	EXP
phosphatidylinositol-4,5-bisphosphate phospholipase C activity	IBA
phosphatidylinositol-4,5-bisphosphate phospholipase C activity	IEA