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Wnt family member 10B
Summary
- Gene Symbol
-
- WNT10B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Developmental protein
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Lipoprotein
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Signal
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| O00744 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G2/M transition of mitotic cell cycle |
|
|
| negative regulation of transcription by RNA polymerase II |
|
|
| osteoblast differentiation |
|
|
| chondrocyte differentiation |
|
|
| transcription by RNA polymerase II |
|
|
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cell cycle [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding |
|
|
| frizzled binding |
|
|
| cytokine activity |
|
|
| protein binding |
|
|
| receptor ligand activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Wnt
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| canonical Wnt signaling pathway |
| cell fate commitment |
| cytokine activity |
| neuron differentiation |
| signaling receptor binding |
| InterPro |
|---|
| Wnt protein, conserved site |
| Wnt, C-terminal domain |
| Wnt |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050591 | tooth agenesis | |
| DOID:0090026 | split hand-foot malformation 6 | |
| DOID:9970 | obesity |
