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Glycan Structure Repository

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Glycoconjugate Repository

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Glycomics MS raw data Repository

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Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

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Tools

Glycan Converters

LM-GlycomeAtlas

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Guidelines

MIRAGE

glyoxylate reductase/hydroxypyruvate reductase

Summary

Gene Symbol

Grhpr

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

76238

KEGG Gene ID

PubChem

76238

Alliance of Genome Resources

MGI:1923488

Annotation

Keyword

Direct protein sequencing
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q91Z53
Q3T9Z2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
monocarboxylic acid metabolic process	IEA
dicarboxylic acid metabolic process	ISO
dicarboxylic acid metabolic process	IEA
glyoxylate metabolic process	ISO
glyoxylate metabolic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

aldehyde metabolic process [inference]

glyoxylate metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process

glyoxylate metabolic process

dicarboxylic acid metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IEA
cytosol	IBA
catalytic complex	ISO
catalytic complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex

cellular anatomical structure [inference]

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
hydroxypyruvate reductase (NADH) activity	ISO
hydroxypyruvate reductase (NADH) activity	IBA
hydroxypyruvate reductase (NADH) activity	IEA
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA
hydroxypyruvate reductase [NAD(P)H] activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

hydroxypyruvate reductase [NAD(P)H] activity

glyoxylate reductase activity

glyoxylate reductase (NADPH) activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

organic acid binding [inference]

carboxylic acid binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADPH binding

NAD binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADPH binding

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111671	primary hyperoxaluria type 2	Alliance of Genome Resources

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	9380	HGNC:4570

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026