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MIRAGE
calcium voltage-gated channel subunit alpha1 B
Summary
- Gene Symbol
-
- CACNA1B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Calcium channel
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Intellectual disability
- Metal-binding
- Methylation
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Transmembrane helix
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| Q00975 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic ion transport |
|
|
| ion transport |
|
|
| chemical synaptic transmission |
|
|
| chemical synaptic transmission |
|
|
| modulation of chemical synaptic transmission |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of neurotransmitter transport [inference]
regulation of vesicle-mediated transport [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| voltage-gated calcium channel complex |
|
|
| voltage-gated calcium channel complex |
|
|
| voltage-gated calcium channel complex |
|
|
| membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| amyloid-beta binding |
|
|
| ion channel activity |
|
|
| monoatomic ion channel activity |
|
|
| voltage-gated calcium channel activity |
|
|
| voltage-gated calcium channel activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- voltage-dependent N-type calcium channel subunit alpha-1B
- Functional Category
-
- E: Amino acid transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050214 | Lambert-Eaton myasthenic syndrome |
