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MIRAGE
calcium voltage-gated channel auxiliary subunit beta 2
Summary
- Gene Symbol
-
- CACNB2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Brugada syndrome
- Calcium channel
- Cell membrane
- Disease variant
- Phosphoprotein
- Proteomics identification
- Reference proteome
- SH3 domain
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| Q08289 |
|
| A0A494C0B2 |
|
| Q59H42 |
|
| A0A494C184 |
|
| Q5VVH1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion transport |
|
|
| chemical synaptic transmission |
|
|
| neuromuscular junction development |
|
|
| visual perception |
|
|
| positive regulation of muscle contraction |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| plasma membrane |
|
|
| voltage-gated calcium channel complex |
|
|
| voltage-gated calcium channel complex |
|
|
| voltage-gated calcium channel complex |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated calcium channel activity |
|
|
| voltage-gated calcium channel activity |
|
|
| calcium channel activity |
|
|
| protein binding |
|
|
| high voltage-gated calcium channel activity |
|
GO Hierarchy
molecular function
transporter activity [inference]
transmembrane transporter activity [inference]
monoatomic ion transmembrane transporter activity [inference]
passive transmembrane transporter activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- voltage-dependent l-type calcium channel subunit
- Functional Category
-
- F: Nucleotide transport and metabolism
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
| Gene Ontology |
|---|
| calcium channel activity |
| calcium ion transmembrane transport |
| calcium ion transport |
| monoatomic ion transport |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110221 | Brugada syndrome 4 | |
| DOID:10763 | hypertension | |
| DOID:11984 | hypertrophic cardiomyopathy |
