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Guidelines

MIRAGE

frizzled class receptor 5

Summary

Gene Symbol

FZD5

Organism

Homo sapiens (human)

External Links

NCBI Gene

7855

KEGG Gene ID

PubChem

7855

Alliance of Genome Resources

HGNC:4043

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Developmental protein
Disulfide bond
G-protein coupled receptor
Glycoprotein
Golgi apparatus
Lipid-binding
Microphthalmia
Proteomics identification
Reference proteome
Signal
Synapse
Transmembrane helix
Ubl conjugation
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q13467	FzE5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 40 in total

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GO Term	Evidence Code	PMID
embryonic axis specification	IDA
angiogenesis
eye development	IMP
glandular epithelial cell maturation
positive regulation of T cell cytokine production	IDA

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

T cell activation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

T cell activation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

apoptotic process involved in development [inference]

apoptotic process involved in morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

neuron differentiation

cell differentiation involved in embryonic placenta development [inference]

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

chorionic trophoblast cell differentiation

cell maturation [inference]

epithelial cell maturation [inference]

columnar/cuboidal epithelial cell maturation [inference]

cellular response to stimulus [inference]

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

cell differentiation involved in embryonic placenta development [inference]

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching involved in labyrinthine layer morphogenesis

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

T cell activation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

pattern specification process [inference]

axis specification [inference]

embryonic axis specification

anterior/posterior axis specification, embryo

anterior/posterior axis specification [inference]

anterior/posterior axis specification, embryo

embryonic pattern specification [inference]

embryonic axis specification

anterior/posterior axis specification, embryo

developmental process [inference]

developmental process involved in reproduction [inference]

cell differentiation involved in embryonic placenta development [inference]

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching involved in labyrinthine layer morphogenesis

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic eye morphogenesis [inference]

embryonic camera-type eye morphogenesis

branching involved in labyrinthine layer morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching involved in labyrinthine layer morphogenesis

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

epithelial cell maturation [inference]

columnar/cuboidal epithelial cell maturation [inference]

anatomical structure formation involved in morphogenesis [inference]

anatomical structure development [inference]

blood vessel development [inference]

placenta blood vessel development [inference]

labyrinthine layer blood vessel development

animal organ development [inference]

sensory organ development [inference]

eye development

camera-type eye development [inference]

post-embryonic camera-type eye development

embryonic organ development [inference]

labyrinthine layer blood vessel development

system development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation in thymus

neuron differentiation

cell differentiation involved in embryonic placenta development [inference]

syncytiotrophoblast cell differentiation involved in labyrinthine layer development

chorionic trophoblast cell differentiation

cell maturation [inference]

epithelial cell maturation [inference]

columnar/cuboidal epithelial cell maturation [inference]

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

cellular response to molecule of bacterial origin

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

cellular response to molecule of bacterial origin

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin

cellular response to stimulus [inference]

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of localization [inference]

regulation of protein localization [inference]

regulation of protein localization to mitochondrion [inference]

positive regulation of protein localization to mitochondrion

positive regulation of protein localization [inference]

positive regulation of protein localization to mitochondrion

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of protein localization [inference]

positive regulation of protein localization to mitochondrion

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of mitophagy

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cell population proliferation [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of bicellular tight junction assembly

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of cellular component organization [inference]

regulation of cell junction assembly [inference]

regulation of bicellular tight junction assembly

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

positive regulation of interleukin-1 beta production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production [inference]

positive regulation of tumor necrosis factor production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production

positive regulation of type II interferon production

positive regulation of interleukin-1 production [inference]

positive regulation of interleukin-1 beta production

positive regulation of tumor necrosis factor superfamily cytokine production [inference]

positive regulation of tumor necrosis factor production

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
Golgi membrane	ISS
Golgi membrane	IEA
early endosome	IEA
Golgi apparatus	IEA
plasma membrane	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

endosome membrane [inference]

early endosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

endocytic vesicle membrane [inference]

clathrin-coated endocytic vesicle membrane

cell junction [inference]

synapse

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

perinuclear region of cytoplasm

Displaying entries **11 - 15** of 19 in total

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GO Term	Evidence Code	PMID
Wnt-protein binding	IEA
protein kinase binding	IPI
ubiquitin protein ligase binding	IPI
Wnt receptor activity	TAS
Wnt receptor activity	IC

GO Hierarchy

molecular function

binding [inference]

protein binding

Wnt-protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

lipid binding

peptide binding [inference]

amyloid-beta binding

protein-containing complex binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	14367	MGI:108571
Rattus norvegicus	317674	RGD:631406
Caenorhabditis elegans	178768	WB:WBGene00000478
Drosophila melanogaster	40090	FB:FBgn0016797
Xenopus laevis	373834	Xenbase:XB-GENE-865299

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026