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Guidelines

MIRAGE

protein tyrosine phosphatase receptor type Fb

Summary

Gene Symbol

ptprfb

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

799867

PubChem

799867

Alliance of Genome Resources

ZFIN:ZDB-GENE-060503-530

Annotation

Keyword

Cell adhesion
Disulfide bond
Glycoprotein
Heparin-binding
Immunoglobulin domain
Protein phosphatase
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

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UniProt	Protein Name
A0A8M3AX63
A4IFW2
A0A8M3AQ61
A0A8M3AQ53
A0A8M3AQ56
A0A8M3APL8
A0A8M3APM3
A0A8M3B074
A0A8M3B7N0
A0A8M3B069

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
protein dephosphorylation	IEA
cell adhesion	IEA
signal transduction	IBA
nervous system development	IBA
dephosphorylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

signal transduction

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

sensory neuron axon guidance

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

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GO Term	Evidence Code	PMID
phosphoprotein phosphatase activity	IEA
protein tyrosine phosphatase activity	IBA
protein tyrosine phosphatase activity	IEA
non-membrane spanning protein tyrosine phosphatase activity	IEA
heparin binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Receptor-type tyrosine-protein phosphatase S

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dephosphorylation
hydrolase activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity

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InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Tursiops truncatus	101317430		TURTR06902
Octodon degus	101572935		OCTDE26299
Jaculus jaculus	101594064		JACJA24582
Mustela putorius furo	101694071		MUSPF18204
Anas platyrhynchos platyrhynchos	101796349		ANAPP20046
Ficedula albicollis	101808677		FICAL07216
Chrysemys picta bellii	101940239		CHRPI37071
Ictidomys tridecemlineatus	101956027		ICTTR09111
Chinchilla lanigera	102029007		CHILA22946
Capra hircus	102180719		CAPHI21550

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025