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Guidelines

MIRAGE

tumor suppressor candidate 3

Summary

Gene Symbol

Tusc3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

80286

PubChem

80286

Alliance of Genome Resources

MGI:1933134

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
Glycoprotein
Magnesium
Proteomics identification
Reference proteome
Signal
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8BTV1	Magnesium uptake/transporter TUSC3 Protein N33 Tumor suppressor candidate 3
A0A7N9VR83

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
cognition	ISS
cognition	ISO
magnesium ion transmembrane transport	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

magnesium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

magnesium ion transport

magnesium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

magnesium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

magnesium ion transmembrane transport

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitochondrion	HDA	14651853
oligosaccharyltransferase complex	ISS
oligosaccharyltransferase complex	ISO
oligosaccharyltransferase complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

oligosaccharyltransferase complex

endoplasmic reticulum protein-containing complex [inference]

oligosaccharyltransferase complex

catalytic complex [inference]

transferase complex [inference]

oligosaccharyltransferase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
magnesium ion transmembrane transporter activity	ISS
magnesium ion transmembrane transporter activity	ISO
oligosaccharyltransferase complex binding

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

magnesium ion transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

magnesium ion transmembrane transporter activity

binding [inference]

protein-containing complex binding [inference]

oligosaccharyltransferase complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tumor suppressor candidate 3

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
protein N-linked glycosylation via asparagine

Displaying **all 2** entries
InterPro
Oligosaccharyl transferase complex, subunit OST3/OST6
Thioredoxin-like superfamily

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	7991	Xenbase:XB-GENE-852905	HUMAN92630
Xenopus tropicalis	34137	Xenbase:XB-GENE-852905
Saccharomyces cerevisiae S288C	67075	SGD:S000005611
Xenopus tropicalis	80286	Xenbase:XB-GENE-852905
Saccharomyces cerevisiae S288C	84061	SGD:S000005611
Saccharomyces cerevisiae S288C	116967	SGD:S000005611
Rattus norvegicus	290783		RATNO11369
Saccharomyces cerevisiae S288C	324944	SGD:S000005611
Pan troglodytes	464002		PANTR42006
Canis lupus familiaris	475608		CANLF04744

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Last updated: December 8, 2025