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actinin alpha 4
Summary
- Gene Symbol
-
- ACTN4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Actin-binding
- Alternative splicing
- Calcium
- Cell junction
- Coiled coil
- Cytoskeleton
- Disease variant
- Metal-binding
- Nucleus
- Phosphoprotein
- Protein transport
- Proteomics identification
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| O43707 |
|
| H7C144 |
|
| F5GXS2 |
|
| A0A0S2Z3G9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein transport |
|
|
| actin cytoskeleton organization |
|
|
| vesicle transport along actin filament |
|
|
| positive regulation of cell migration |
|
|
| positive regulation of sodium:proton antiporter activity |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| stress fiber |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| obsolete extracellular space |
|
|
| nucleus |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II transcription regulatory region sequence-specific DNA binding |
|
|
| nucleoside binding |
|
|
| transcription coactivator activity |
|
|
| RNA binding |
|
|
| actin binding |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Alpha actinin
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin binding |
| actin cytoskeleton organization |
| actin filament binding |
| calcium ion binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111128 | focal segmental glomerulosclerosis 1 | |
| DOID:1312 | focal segmental glomerulosclerosis |
