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MIRAGE
LAS1 like ribosome biogenesis factor
Summary
- Gene Symbol
-
- LAS1L
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasm
- Disease variant
- Hydrolase
- Intellectual disability
- Isopeptide bond
- Nucleus
- Obesity
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Ubl conjugation
- rRNA processing
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A7I2YQI7 |
|
| A0A7I2V653 |
|
| Q9Y4W2 |
|
| A0A7I2V3R6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
|
|
| maturation of 5.8S rRNA |
|
|
| maturation of LSU-rRNA |
|
|
| rRNA processing |
|
|
| rRNA processing |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| nucleus |
|
|
| nucleoplasm |
|
|
| nucleoplasm |
|
|
| nucleolus |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA binding |
|
|
| endonuclease activity |
|
|
| protein binding |
|
|
| hydrolase activity |
|
|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060814 | Wilson-Turner syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 76130 | MGI:1923380 |
