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N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

Summary

Gene Symbol

Ndst3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

83398

KEGG Gene ID

mmu:83398

PubChem

83398

Alliance of Genome Resources

MGI:1932544

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycoprotein
Golgi apparatus
Hydrolase
Multifunctional enzyme
Proteomics identification
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
D3YXE5
Q9EQH7	Glucosaminyl N-deacetylase/N-sulfotransferase 3 N-heparan sulfate sulfotransferase 3
E9PZJ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
heparan sulfate proteoglycan biosynthetic process	ISO
heparan sulfate proteoglycan biosynthetic process	IMP
heparan sulfate proteoglycan biosynthetic process	IBA
heparan sulfate proteoglycan biosynthetic process	IEA
heparin proteoglycan biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparin proteoglycan metabolic process [inference]

heparin proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparin proteoglycan metabolic process [inference]

heparin proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

heparin proteoglycan metabolic process [inference]

heparin proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process [inference]

heparan sulfate proteoglycan biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
Golgi apparatus	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
sulfotransferase activity	IDA
sulfotransferase activity	IEA
heparan sulfate N-sulfotransferase activity	ISO
heparan sulfate N-sulfotransferase activity	IDA
heparan sulfate N-sulfotransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity

proteoglycan sulfotransferase activity [inference]

heparan sulfate sulfotransferase activity [inference]

heparan sulfate N-sulfotransferase activity

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

heparan sulfate N-deacetylase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

N-acetylglucosamine deacetylase activity

deacylase activity [inference]

deacetylase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K02578

Name

heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.5.1.- 2.8.2.8]

References

9915799

Rhea

RHEA:21980

3'-phosphoadenylyl sulfate

H⁺ + adenosine 3',5'-bisphosphate

Enzyme

2.8.2.8

PMID

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	295430	RGD:1310960
Caenorhabditis elegans	177675	WB:WBGene00002028
Drosophila melanogaster	38736	FB:FBgn0020251
Homo sapiens	9348	HGNC:7682
Danio rerio	100317129	ZFIN:ZDB-GENE-090312-199
Xenopus tropicalis	100145653	Xenbase:XB-GENE-1001604