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slit guidance ligand 3

Summary

Gene Symbol

Slit3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

83467

KEGG Gene ID

PubChem

83467

Alliance of Genome Resources

RGD:69311

Annotation

Keyword

Developmental protein
Differentiation
Disulfide bond
EGF-like domain
Glycoprotein
Leucine-rich repeat
Neurogenesis
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O88280	Multiple epidermal growth factor-like domains protein 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
aortic valve morphogenesis	ISO
atrioventricular valve morphogenesis	ISO
axon guidance	ISO
axon guidance	IBA
negative regulation of cell population proliferation	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Roundabout signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

apoptotic process involved in development [inference]

apoptotic process involved in luteolysis

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

developmental process [inference]

anatomical structure morphogenesis [inference]

heart valve morphogenesis [inference]

animal organ morphogenesis

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

anatomical structure development [inference]

spinal cord development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

axon extension [inference]

axon extension involved in axon guidance

locomotion [inference]

taxis [inference]

chemotaxis [inference]

negative chemotaxis

chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus

response to chemical [inference]

response to hormone [inference]

cellular response to hormone stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to cortisol

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to cortisol

response to ketone [inference]

response to cortisol

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to hormone stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of cell growth

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Roundabout signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of chemokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of chemokine-mediated signaling pathway

negative regulation of cell growth

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	IEA
obsolete extracellular space
cell junction	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
heparin binding	IBA
Roundabout binding	ISO
Roundabout binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

Roundabout binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	20564	MGI:1315202
Drosophila melanogaster	36746	FB:FBgn0264089
Homo sapiens	6586	HGNC:11087

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