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Guidelines

MIRAGE

solute carrier family 25 member 11

Summary

Gene Symbol

SLC25A11

Organism

Homo sapiens (human)

External Links

NCBI Gene

8402

KEGG Gene ID

PubChem

8402

Alliance of Genome Resources

HGNC:10981

Annotation

Keyword

Acetylation
Alternative splicing
Antiport
Direct protein sequencing
Disease variant
Lipid transport
Mitochondrion inner membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q02978	Solute carrier family 25 member 11
Q6IBH0	Solute carrier family 25 member 11

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
gluconeogenesis	IEA
lipid transport
alpha-ketoglutarate transport	IEA
malate-aspartate shuttle	IMP
malate-aspartate shuttle	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

pyridine-containing compound metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD+ metabolic process [inference]

malate-aspartate shuttle

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

carboxylic acid transmembrane transport [inference]

malate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

lipid transport

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

malate transport [inference]

malate transmembrane transport

alpha-ketoglutarate transport

carboxylic acid transmembrane transport [inference]

malate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

malate transport [inference]

malate transmembrane transport

alpha-ketoglutarate transport

carboxylic acid transmembrane transport [inference]

malate transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

carboxylic acid transmembrane transport [inference]

malate transmembrane transport

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleus	HDA
mitochondrion	HTP
mitochondrion	HDA
mitochondrial inner membrane	TAS
mitochondrial inner membrane	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA
protein binding	IPI
proton transmembrane transporter activity	ISS
proton transmembrane transporter activity	IEA
alpha-ketoglutarate transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

oxoglutarate:malate antiporter activity

carboxylic acid transmembrane transporter activity [inference]

dicarboxylic acid transmembrane transporter activity [inference]

alpha-ketoglutarate transmembrane transporter activity

oxoglutarate:malate antiporter activity

malate transmembrane transporter activity [inference]

oxoglutarate:malate antiporter activity

C4-dicarboxylate transmembrane transporter activity [inference]

malate transmembrane transporter activity [inference]

oxoglutarate:malate antiporter activity

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mitochondrial uncoupling protein

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Mitochondrial carrier domain superfamily
Mitochondrial carrier protein
Mitochondrial substrate/solute carrier

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050773	paraganglioma	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	67863	MGI:1915113
Rattus norvegicus	64201	RGD:708476

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026