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THO complex subunit 3

Summary

Gene Symbol

THOC3

Organism

Homo sapiens (human)

External Links

NCBI Gene

84321

PubChem

84321

Alliance of Genome Resources

HGNC:19072

JoGo

THOC3

TogoVar

THOC3

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Nucleus
Proteomics identification
RNA-binding
Reference proteome
Repeat
WD repeat
mRNA splicing
mRNA transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96J01	TEX1 homolog hTREX45

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mRNA processing
mRNA export from nucleus	NAS	33191911
mRNA export from nucleus	IDA	17190602
mRNA export from nucleus	IBA	http://purl.obolibrary.org/obo/go/references/0000033
mRNA export from nucleus	IEA	http://purl.obolibrary.org/obo/go/references/0000002

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

RNA processing [inference]

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

localization [inference]

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
transcription export complex	NAS	33191911
transcription export complex	IDA	15833825 15998806
THO complex part of transcription export complex	IDA	23222130
THO complex part of transcription export complex	IBA	http://purl.obolibrary.org/obo/go/references/0000033
chromosome, telomeric region	IDA	24270157

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

transcription export complex

THO complex [inference]

THO complex part of transcription export complex

cellular anatomical structure [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

chromosomal region [inference]

chromosome, telomeric region

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying 1 entry
GO Term	Evidence Code	PMID
RNA binding

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

THO complex subunit 3

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
mRNA export from nucleus

Displaying **all 7** entries
InterPro
Anaphase-promoting complex subunit 4-like, WD40 domain
G-protein beta WD-40 repeat
TREX component Tex1/THOC3
WD40 repeat
WD40-like beta propeller
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily