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protein phosphatase regulator SHP1

Summary

Gene Symbol

SHP1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

852222

KEGG Gene ID

PubChem

852222

Alliance of Genome Resources

SGD:S000000154

Annotation

Keyword

3D-structure
Cytoplasm
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P34223	Suppressor of high-copy PP1 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
autophagosome assembly	IMP
autophagosome assembly	IBA
glycogen metabolic process	IMP
Golgi organization	IBA
ascospore formation	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

cell cycle process [inference]

attachment of spindle microtubules to kinetochore [inference]

sister chromatid biorientation

meiotic cell cycle process [inference]

ascospore formation

protein unfolding

cellular developmental process [inference]

cell development [inference]

ascospore formation

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

membrane assembly [inference]

nuclear membrane reassembly

membrane organization [inference]

membrane fusion

membrane assembly [inference]

nuclear membrane reassembly

nuclear membrane organization [inference]

nuclear membrane reassembly

reproductive process [inference]

developmental process involved in reproduction [inference]

sexual sporulation [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

reproductive process in single-celled organism [inference]

ascospore formation

meiotic cell cycle process [inference]

ascospore formation

developmental process [inference]

developmental process involved in reproduction [inference]

sexual sporulation [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

sporulation [inference]

sporulation resulting in formation of a cellular spore [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

sexual sporulation [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

anatomical structure formation involved in morphogenesis [inference]

sporulation resulting in formation of a cellular spore [inference]

sexual sporulation resulting in formation of a cellular spore [inference]

ascospore formation

anatomical structure development [inference]

cell development [inference]

ascospore formation

cellular developmental process [inference]

cell development [inference]

ascospore formation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

response to chemical [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

ERAD pathway

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
nucleus	IEA
nucleus	HDA
cytoplasm	IEA
cytoplasm	HDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI
protein phosphatase regulator activity	IMP
K48-linked polyubiquitin modification-dependent protein binding	IDA
ubiquitin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

ubiquitin-like protein binding [inference]

ubiquitin binding

modification-dependent protein binding [inference]

polyubiquitin modification-dependent protein binding [inference]

K48-linked polyubiquitin modification-dependent protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

phosphatase regulator activity [inference]

protein phosphatase regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

UBX domain-containing protein

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
Golgi organization
autophagosome assembly
nuclear membrane reassembly
proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin binding

Displaying **all 5** entries
InterPro
NSFL1 cofactor p47, SEP domain superfamily
SEP domain
UBA-like superfamily
UBX domain
Ubiquitin-like domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
nucleus	PMID:14562095 PMID:26928762
cytosol	PMID:26928762
cytoplasm	PMID:14562095

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	35674	FB:FBgn0033179

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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OrthoDB (Group)

International Collaboration

Acknowledgements