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cyclic nucleotide gated channel subunit alpha 1

Summary

Gene Symbol

Cnga1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

85259

KEGG Gene ID

PubChem

85259

Alliance of Genome Resources

RGD:621815

Annotation

Keyword

Calcium channel
Cell membrane
Coiled coil
Glycoprotein
Ligand-gated ion channel
Reference proteome
Sodium channel
Transmembrane helix
Vision
cAMP-binding
cGMP-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q62927	Cyclic nucleotide-gated cation channel 1 Cyclic nucleotide-gated channel, photoreceptor Rod photoreceptor cGMP-gated cation channel subunit alpha cGMP-gated cation channel alpha-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
monoatomic ion transport	IEA
ion transport	IEA
sodium ion transport	ISS
calcium ion transport	ISS
spermatogenesis	IEP

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus

sensory perception of light stimulus [inference]

visual perception

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

metal ion transport [inference]

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

membrane depolarization

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	ISO
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

cellular anatomical structure [inference]

photoreceptor outer segment

rod photoreceptor outer segment

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

cell projection [inference]

plasma membrane bounded cell projection

presynapse [inference]

terminal bouton

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
ion channel activity	IEA
monoatomic ion channel activity	IEA
intracellularly cyclic nucleotide-activated monoatomic cation channel activity	TAS
intracellularly cyclic nucleotide-activated monoatomic cation channel activity	IEA
intracellularly cAMP-activated cation channel activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

intracellularly ligand-gated monoatomic ion channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

calcium ion transmembrane transporter activity [inference]

calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

intracellularly ligand-gated monoatomic ion channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

intracellularly ligand-gated monoatomic ion channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellularly cyclic nucleotide-activated monoatomic cation channel activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

cAMP binding

guanyl ribonucleotide binding [inference]

cGMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cyclic nucleotide-gated cation channel

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cGMP binding
intracellular cAMP-activated cation channel activity
intracellular cGMP-activated cation channel activity
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 5** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Cyclic nucleotide-binding domain
Cyclic nucleotide-binding, conserved site
Ion transport domain
RmlC-like jelly roll fold