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Doa1p

Summary

Gene Symbol

DOA1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853667

KEGG Gene ID

PubChem

853667

Alliance of Genome Resources

SGD:S000001696

Annotation

Keyword

3D-structure
Cytoplasm
Direct protein sequencing
Endosome
Mitochondrion outer membrane
Nucleus
Phosphoprotein
Reference proteome
Repeat
Ubl conjugation pathway
WD repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
P36037	Degradation of alpha protein 1 Ubiquitin fusion degradation protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
double-strand break repair via break-induced replication	IDA
double-strand break repair via nonhomologous end joining	IMP
ubiquitin recycling	IMP
ubiquitin recycling	IBA
ribophagy	IMP

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

ribophagy

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair via nonhomologous end joining

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

mitochondria-associated ubiquitin-dependent protein catabolic process

cell cycle process [inference]

G1 to G0 transition

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair via nonhomologous end joining

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

ribophagy

homeostatic process [inference]

cellular homeostasis [inference]

ubiquitin recycling

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair via nonhomologous end joining

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair [inference]

double-strand break repair via homologous recombination [inference]

double-strand break repair via break-induced replication

double-strand break repair via nonhomologous end joining

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
nucleus	EXP
nucleus	IDA
nucleus	IBA
nucleus	IEA
nucleus	HDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

endosome membrane

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of mitochondrial outer membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
K48-linked polyubiquitin modification-dependent protein binding	IDA
ubiquitin binding	IDA
ubiquitin binding	IMP
ubiquitin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

ubiquitin-like protein binding [inference]

ubiquitin binding

modification-dependent protein binding [inference]

polyubiquitin modification-dependent protein binding [inference]

K48-linked polyubiquitin modification-dependent protein binding

protein-containing complex binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

ubiquitin-like protein reader activity [inference]

ubiquitin-modified protein reader activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phospholipase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
proteasome-mediated ubiquitin-dependent protein catabolic process
ubiquitin binding

Displaying **all 7** entries
InterPro
Armadillo-like helical
PFU domain superfamily
PLAA family ubiquitin binding domain
PUL domain
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily