GlyCosmos Portal

Submissions

sphingosine N-acyltransferase LAC1

Summary

Gene Symbol

LAC1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

853861

KEGG Gene ID

PubChem

853861

Alliance of Genome Resources

SGD:S000001491

Annotation

Keyword

3D-structure
Acetylation
Endoplasmic reticulum
Glycoprotein
Lipid biosynthesis
Phosphoprotein
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P28496	Very-long-chain ceramide synthase LAC1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sphingolipid metabolic process	IEA
ceramide biosynthetic process	IDA
ceramide biosynthetic process	IMP
ceramide biosynthetic process	IBA
ceramide biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

ceramide biosynthetic process

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA
endoplasmic reticulum	IBA
endoplasmic reticulum membrane	IEA
membrane	IEA
nuclear periphery	HDA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

acyl-CoA ceramide synthase complex

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

nuclear periphery

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
protein binding	IPI
sphingosine N-acyltransferase activity	RCA
sphingosine N-acyltransferase activity	IDA
sphingosine N-acyltransferase activity	IMP
sphingosine N-acyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

N-acyltransferase activity [inference]

sphingosine N-acyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
endoplasmic reticulum	PMID:10198056
acyl-CoA ceramide synthase complex	PMID:15692566
nuclear periphery	PMID:26928762

Ortholog

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources
Mus musculus	67260	MGI:1914510
Mus musculus	76893	MGI:1924143
Mus musculus	241447	MGI:2442564
Mus musculus	71949	MGI:1919199
Caenorhabditis elegans	180743	WB:WBGene00002044
Homo sapiens	204219	HGNC:23752
Homo sapiens	79603	HGNC:23747
Homo sapiens	29956	HGNC:14076
Homo sapiens	91012	HGNC:23749
Homo sapiens	10715	HGNC:14253