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Rho family GTPase RHO1

Summary

Gene Symbol

RHO1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856294

KEGG Gene ID

PubChem

856294

Alliance of Genome Resources

SGD:S000006369

Annotation

Keyword

3D-structure
Acetylation
Cell membrane
Direct protein sequencing
Endosome
GTP-binding
Hydrolase
Methylation
Peroxisome
Prenylation
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P06780	Rho-type GTPase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **21 - 25** of 27 in total

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GO Term	Evidence Code	PMID
regulation of exocyst localization	IMP
regulation of fungal-type cell wall organization	IMP
regulation of cell wall (1->3)-beta-D-glucan biosynthetic process	IDA
regulation of cell wall (1->3)-beta-D-glucan biosynthetic process	IMP
regulation of secondary cell septum biogenesis	IMP

GO Hierarchy

biological process

cellular process [inference]

signal transduction

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

glucan metabolic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan metabolic process [inference]

(1->3)-beta-D-glucan metabolic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

macromolecule biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

glucan metabolic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan metabolic process [inference]

(1->3)-beta-D-glucan metabolic process [inference]

(1->3)-beta-D-glucan biosynthetic process

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

carbohydrate biosynthetic process [inference]

polysaccharide biosynthetic process [inference]

glucan biosynthetic process [inference]

beta-glucan biosynthetic process [inference]

(1->3)-beta-D-glucan biosynthetic process

cell cycle process [inference]

meiotic cell cycle process [inference]

ascospore wall assembly

mitotic cell cycle process [inference]

cellular bud neck septin ring organization

actin filament-based process [inference]

actin cytoskeleton organization

cell wall organization or biogenesis [inference]

cell wall biogenesis [inference]

fungal-type cell wall biogenesis

cell wall organization [inference]

fungal-type cell wall organization [inference]

fungal-type cell wall assembly [inference]

ascospore wall assembly

cell wall assembly [inference]

spore wall assembly [inference]

ascospore wall assembly

fungal-type cell wall assembly [inference]

ascospore wall assembly

fungal-type cell wall organization or biogenesis [inference]

fungal-type cell wall biogenesis

fungal-type cell wall organization [inference]

fungal-type cell wall assembly [inference]

ascospore wall assembly

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

septin cytoskeleton organization [inference]

septin ring organization [inference]

cellular bud neck septin ring organization

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

spore wall assembly [inference]

ascospore wall assembly

cell wall assembly [inference]

spore wall assembly [inference]

ascospore wall assembly

fungal-type cell wall assembly [inference]

ascospore wall assembly

regulation of cellular component size [inference]

regulation of cell size

external encapsulating structure organization [inference]

cell wall organization [inference]

fungal-type cell wall organization [inference]

fungal-type cell wall assembly [inference]

ascospore wall assembly

cell wall assembly [inference]

spore wall assembly [inference]

ascospore wall assembly

fungal-type cell wall assembly [inference]

ascospore wall assembly

supramolecular fiber organization [inference]

actin filament organization

cellular component biogenesis [inference]

cell wall biogenesis [inference]

fungal-type cell wall biogenesis

reproductive process [inference]

developmental process involved in reproduction [inference]

ascospore wall assembly

meiotic cell cycle process [inference]

ascospore wall assembly

developmental process [inference]

developmental process involved in reproduction [inference]

ascospore wall assembly

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

spore wall assembly [inference]

ascospore wall assembly

growth [inference]

budding cell bud growth

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of exocyst localization

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of endocytosis

positive regulation of cell division [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of transport [inference]

positive regulation of endocytosis

regulation of cellular process [inference]

signal transduction

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of cell wall macromolecule metabolic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of beta-glucan metabolic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of polysaccharide metabolic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of beta-glucan metabolic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of carbohydrate biosynthetic process [inference]

regulation of polysaccharide biosynthetic process [inference]

regulation of glucan biosynthetic process [inference]

regulation of beta-glucan biosynthetic process [inference]

regulation of (1->3)-beta-D-glucan biosynthetic process [inference]

regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of actomyosin structure organization [inference]

regulation of cytokinesis, actomyosin contractile ring assembly [inference]

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of cellular component biogenesis [inference]

regulation of secondary cell septum biogenesis

regulation of cytokinesis, actomyosin contractile ring assembly [inference]

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of endocytosis

positive regulation of cell division [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of vacuole organization [inference]

regulation of vacuole fusion, non-autophagic

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of actomyosin structure organization [inference]

regulation of cytokinesis, actomyosin contractile ring assembly [inference]

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytoskeleton organization [inference]

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of endocytosis

regulation of fungal-type cell wall organization

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of mitotic cytokinesis [inference]

regulation of mitotic cytokinetic process [inference]

regulation of secondary cell septum biogenesis

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cell division [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of mitotic cytokinesis [inference]

regulation of mitotic cytokinetic process [inference]

regulation of secondary cell septum biogenesis

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of cytokinetic process [inference]

regulation of mitotic cytokinetic process [inference]

regulation of secondary cell septum biogenesis

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of cytokinesis, actomyosin contractile ring assembly [inference]

regulation of mitotic actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic actomyosin contractile ring assembly

positive regulation of cytokinesis, actomyosin contractile ring assembly [inference]

positive regulation of mitotic actomyosin contractile ring assembly

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of cell wall organization or biogenesis [inference]

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
incipient cellular bud site	IDA
1,3-beta-D-glucan synthase complex	IDA
1,3-beta-D-glucan synthase complex	IPI
fungal-type vacuole membrane	IDA
mitochondrion	HDA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

1,3-beta-D-glucan synthase complex

cellular anatomical structure [inference]

membrane

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

fungal-type vacuole membrane

endosome membrane

microbody membrane [inference]

peroxisomal membrane

organelle outer membrane [inference]

mitochondrial outer membrane

external encapsulating structure [inference]

cell wall [inference]

site of polarized growth [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

cell pole [inference]

cell tip [inference]

mating projection tip

cell periphery

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISS
GTPase activity	IDA
GTPase activity	IBA
GTPase activity	IEA
G protein activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

G protein activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

G-protein beta-subunit binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

molecular function regulator activity [inference]

G protein activity

enzyme regulator activity [inference]

enzyme activator activity

molecular function activator activity [inference]

enzyme activator activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying entries **1 - 10** of 14 in total

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Location	References
plasma membrane	PMID:16622836
fungal-type vacuole membrane	PMID:11598008
endoplasmic reticulum	PMID:26928762
cellular bud tip	PMID:8195291
Golgi apparatus	PMID:1918143
mitochondrion	PMID:14576278 PMID:16823961 PMID:24769239
1,3-beta-D-glucan synthase complex	PMID:8602515
peroxisome	PMID:15596542
mitochondrial outer membrane	PMID:16407407
cellular bud neck	PMID:8195291

Rhea

RHEA:19669

H₂O + GTP

H⁺ + phosphate + GDP

Enzyme

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:8577	ulcerative colitis	Alliance of Genome Resources

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	388	HGNC:668
Homo sapiens	387	HGNC:667
Homo sapiens	389	HGNC:669
Danio rerio	406659	ZFIN:ZDB-GENE-040426-2665
Danio rerio	100006041	ZFIN:ZDB-GENE-040322-2
Danio rerio	436718	ZFIN:ZDB-GENE-040718-144
Danio rerio	406411	ZFIN:ZDB-GENE-040426-2150

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

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Acknowledgements