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putative ATP-binding cassette multidrug transporter VMR1

Summary

Gene Symbol

VMR1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856350

KEGG Gene ID

PubChem

856350

Alliance of Genome Resources

SGD:S000001027

Annotation

Keyword

ATP-binding
Glycoprotein
Reference proteome
Repeat
Transmembrane helix
Transport
Vacuole

Proteins

Displaying 1 entry
UniProt	Protein Name
P38735	Vacuolar multidrug resistance protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
response to metal ion	IMP
xenobiotic transport	IEA
transmembrane transport	IBA
transmembrane transport	IEA
xenobiotic detoxification by transmembrane export across the plasma membrane	IMP

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

response to stimulus [inference]

response to chemical [inference]

response to metal ion

localization [inference]

establishment of localization [inference]

transport [inference]

xenobiotic transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
fungal-type vacuole membrane	IDA
fungal-type vacuole membrane	IBA
fungal-type vacuole membrane	IEA
mitochondrion	HDA
vacuolar membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane

lytic vacuole membrane [inference]

fungal-type vacuole membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ATP binding	IEA
ABC-type xenobiotic transporter activity	ISA
ATP hydrolysis activity	IEA
ABC-type transporter activity	IBA
ABC-type transporter activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

ABC-type xenobiotic transporter activity

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

ABC-type xenobiotic transporter activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
mitochondrion	PMID:14576278 PMID:16823961
fungal-type vacuole membrane	PMID:20846144 PMID:23658021

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	89845	HGNC:52

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Last updated: April 6, 2026

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