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chromatin-remodeling ATPase CHD1

Summary

Gene Symbol

CHD1

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

856911

PubChem

856911

Alliance of Genome Resources

SGD:S000000966

Annotation

Keyword

3D-structure
ATP-binding
Chromatin regulator
DNA-binding
Hydrolase
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P32657	Chromo domain-containing protein 1 Chromodomain helicase-like DNA-binding protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
double-strand break repair via homologous recombination	IMP
DNA double-strand break processing	IMP
regulation of transcriptional start site selection at RNA polymerase II promoter	IGI
chromatin remodeling	IDA
regulation of transcription by RNA polymerase II	NAS

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA double-strand break processing

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA double-strand break processing

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription termination [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cell cycle process [inference]

sister chromatid cohesion

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling

nucleosome organization

organelle organization [inference]

chromosome organization [inference]

sister chromatid cohesion

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

nucleosome organization

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

double-strand break repair [inference]

double-strand break repair via homologous recombination

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of DNA-templated DNA replication [inference]

negative regulation of DNA-templated DNA replication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of transcription, start site selection [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of DNA-templated DNA replication [inference]

negative regulation of DNA-templated DNA replication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

regulation of transcriptional start site selection at RNA polymerase II promoter

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication

regulation of cellular component organization [inference]

regulation of chromatin organization

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
SAGA complex	IDA
SAGA complex	IPI
chromatin	IDA
chromatin	IBA
nucleus	EXP

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

protein acetyltransferase complex [inference]

histone acetyltransferase complex [inference]

SAGA-type complex [inference]

catalytic complex [inference]

peptidase complex [inference]

SAGA complex

transferase complex [inference]

acetyltransferase complex [inference]

protein acetyltransferase complex [inference]

histone acetyltransferase complex [inference]

SAGA-type complex [inference]

cellular anatomical structure [inference]

chromatin

nucleolar chromatin

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

site of DNA damage [inference]

site of double-strand break

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
rDNA binding	IDA
transcription cis-regulatory region binding	IDA
DNA binding	IDA
DNA binding	IBA
chromatin binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

ATP-dependent chromatin remodeler activity

histone octamer slider activity [inference]

nucleosome array spacer activity

binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding

DNA binding

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

chromatin DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

chromatin binding

chromatin DNA binding

protein binding [inference]

histone binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

chromatin-protein adaptor activity [inference]

histone reader activity [inference]

histone H3 reader activity [inference]

histone H3K4me3 reader activity

ATP-dependent activity [inference]

ATP-dependent activity, acting on DNA

ATP-dependent chromatin remodeler activity

histone octamer slider activity [inference]

nucleosome array spacer activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

chromodomain helicase

Functional Category

C: Energy production and conversion
L: Replication, recombination and repair
V: Defense mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
chromatin binding
histone binding
hydrolase activity
nucleosome organization
nucleotide binding

Displaying **all 10** entries
InterPro
Chromo domain
Chromo-like domain superfamily
Chromo/chromo shadow domain
Chromodomain-helicase-DNA-binding protein 1-like, C-terminal domain
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
P-loop containing nucleoside triphosphate hydrolase
SNF2, N-terminal
SNF2-like, N-terminal domain superfamily
SNF2/RAD5-like, C-terminal helicase domain

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
chromatin	PMID:12504018 PMID:12682017
site of double-strand break	PMID:34520455
mitochondrion	PMID:14576278 PMID:16823961
nucleolar chromatin	PMID:17259992
SAGA complex	PMID:15647753
SLIK (SAGA-like) complex	PMID:15647753

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10283	prostate cancer	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements