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MIRAGE
fructose-bisphosphatase 2

Summary
Gene Symbol
  • FBP2
Organism
Homo sapiens (human)
NCBI Gene
8789
HGNC
3607
KEGG Gene ID
PubChem
8789
Alliance of Genome Resources
JoGo
FBP2
TogoVar
FBP2
Annotation
Keyword
  • 3D-structure
  • Allosteric enzyme
  • Calcium
  • Carbohydrate metabolism
  • Cell junction
  • Cytoplasm
  • Disease variant
  • Gluconeogenesis
  • Hydrolase
  • Leukodystrophy
  • Magnesium
  • Metal-binding
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
O00757
  • D-fructose-1,6-bisphosphate 1-phosphohydrolase 2
  • Muscle FBPase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
carbohydrate metabolic process
fructose metabolic process
fructose metabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K03841
Name
fructose-1,6-bisphosphatase I [EC:3.1.3.11]
References
Rhea

RHEA:11064

H2O + β-D-fructose 1,6-bisphosphate
phosphate + β-D-fructose 6-phosphate
Enzyme
PMID
Disease
The Human Phenotype Ontology
Displaying all 8 entries
HPO ID HPO Term
HP:0000006 Autosomal dominant inheritance
HP:0000737 Irritability
HP:0001288 Gait disturbance
HP:0002415 Leukodystrophy
HP:0002500 Abnormal cerebral white matter morphology
HP:0003593 Infantile onset
HP:0007359 Focal-onset seizure
HP:0011968 Feeding difficulties
Displaying 1 entry
Disease ID Disease Name
OMIM:619864
  • leukodystrophy, childhood-onset, remitting
PubChem Disease
MedGen Diseases
OMIM Phenotypes
Gene-Disease-Co-Occurrences-in-Literature (PubChem)
Ortholog
Displaying all 3 entries
Species Gene ID Alliance of Genome Resources
14120 MGI:95491
114508 RGD:620930
851092 SGD:S000004369
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026