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Guidelines

MIRAGE

solute carrier family 5 member 6

Summary

Gene Symbol

SLC5A6

Organism

Homo sapiens (human)

External Links

NCBI Gene

8884

KEGG Gene ID

PubChem

8884

Alliance of Genome Resources

HGNC:11041

Annotation

Keyword

Biotin
Cell membrane
Disease variant
Glycoprotein
Neurodegeneration
Neuropathy
Proteomics identification
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9Y289	Solute carrier family 5 member 6
Q9HD19

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
biotin metabolic process	IEA
sodium ion transport	IBA
biotin transport	IDA
biotin transport	IMP
biotin transport	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

sulfur compound metabolic process [inference]

biotin metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

biotin metabolic process

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

vitamin transmembrane transport [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biotin import across plasma membrane

carboxylic acid transmembrane transport [inference]

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transport [inference]

iodide transport [inference]

iodide transmembrane transport

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

inorganic anion transport [inference]

iodide transport [inference]

iodide transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

biotin transport

biotin import across plasma membrane

pantothenate transmembrane transport

carboxylic acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

biotin transport

biotin import across plasma membrane

pantothenate transmembrane transport

carboxylic acid transmembrane transport [inference]

vitamin transport [inference]

biotin transport

biotin import across plasma membrane

vitamin transmembrane transport [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

vitamin transmembrane transport [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biotin import across plasma membrane

carboxylic acid transmembrane transport [inference]

nitrogen compound transport [inference]

biotin transport

biotin import across plasma membrane

modified amino acid transport [inference]

pantothenate transmembrane transport

sulfur compound transport [inference]

biotin transport

biotin import across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biotin import across plasma membrane

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
plasma membrane	EXP
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

brush border membrane

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
sodium-dependent multivitamin transmembrane transporter activity	TAS
sodium-dependent multivitamin transmembrane transporter activity	IBA
sodium-dependent multivitamin transmembrane transporter activity	IEA
monoatomic ion transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

monoatomic ion transmembrane transporter activity

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

monoatomic anion transmembrane transporter activity [inference]

iodide transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

biotin transmembrane transporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

modified amino acid transmembrane transporter activity [inference]

vitamin transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

biotin transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

solute carrier family 5 member 5

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sodium/glucose symporter superfamily
Sodium/solute symporter

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	330064	MGI:2660847
Rattus norvegicus	170551	RGD:69648
Drosophila melanogaster	326229	FB:FBgn0052669

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026