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MIRAGE

endonuclease VIII Nei2

Summary

Gene Symbol

nei2

Organism

Mycolicibacterium smegmatis

External Links

NCBI Gene: 93456573
KEGG Gene ID: [""]
PubChem: 93456573

Annotation

Keyword

3D-structure
DNA repair
DNA-binding
Endonuclease
Glycosidase
Lyase
Multifunctional enzyme
Reference proteome
Zinc-finger

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A2U9PM01
A0A653FLZ5
A0QT90	Endonuclease 8 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
base-excision repair	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

base-excision repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

base-excision repair

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

base-excision repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

base-excision repair

Displaying **all 5** entries
GO Term	Evidence Code	PMID
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	IEA
damaged DNA binding	IEA
zinc ion binding	IEA
class I DNA-(apurinic or apyrimidinic site) endonuclease activity	EXP
class I DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity [inference]

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

lyase activity [inference]

carbon-oxygen lyase activity [inference]

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

catalytic activity, acting on a nucleic acid [inference]

nuclease activity [inference]

endonuclease activity [inference]

DNA endonuclease activity [inference]

DNA-(apurinic or apyrimidinic site) endonuclease activity [inference]

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

DNA nuclease activity [inference]

DNA endonuclease activity [inference]

DNA-(apurinic or apyrimidinic site) endonuclease activity [inference]

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA endonuclease activity [inference]

DNA-(apurinic or apyrimidinic site) endonuclease activity [inference]

class I DNA-(apurinic or apyrimidinic site) endonuclease activity

DNA N-glycosylase activity [inference]

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026