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MIRAGE
Rho associated coiled-coil containing protein kinase 2
Summary
- Gene Symbol
-
- ROCK2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Biological rhythms
- Cell membrane
- Coiled coil
- Cytoskeleton
- Magnesium
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Serine/threonine-protein kinase
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A2P9DU05 |
|
| O75116 |
|
| Q14DU5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitotic cytokinesis | ||
| epithelial to mesenchymal transition | ||
| response to ischemia | ||
| aortic valve morphogenesis | ||
| protein phosphorylation |
GO Hierarchy
- rhythmic process
- regulation of circadian rhythm
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protease binding | ||
| RNA binding | ||
| protein kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- rho-associated protein kinase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| Rho protein signal transduction |
| Rho-dependent protein serine/threonine kinase activity |
| actin cytoskeleton organization |
| actomyosin structure organization |
| kinase activity |
| metal ion binding |
| mitotic cytokinesis |
| nucleotide binding |
| phosphorylation |
