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galactose-3-O-sulfotransferase 1

Summary

Gene Symbol

GAL3ST1

Aliases

CST
cerebroside (3' phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

9514

GGDB ID

gg041

HGNC

24240

mRNA

NM_004861

map

22q12.2

Protein

NP_004852

OMIM

602300

KEGG Gene ID

hsa:9514

PubChem

9514

Alliance of Genome Resources

HGNC:24240

JoGo

GAL3ST1

TogoVar

GAL3ST1

Annotation

Keyword

Direct protein sequencing
Glycoprotein
Golgi apparatus
Proteomics identification
Reference proteome
Signal-anchor
Sphingolipid metabolism
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q99999	3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase Cerebroside sulfotransferase
B2R7S4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein N-linked glycosylation	TAS
sphingolipid metabolic process	IDA
sphingolipid metabolic process	IEA
galactosylceramide metabolic process	ISS
galactosylceramide metabolic process	IEA

GO Hierarchy

biological process

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

metabolic process [inference]

biosynthetic process [inference]

lipid biosynthetic process [inference]

glycolipid biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

ceramide biosynthetic process [inference]

galactosylceramide biosynthetic process

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

glycolipid biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

primary metabolic process [inference]

lipid metabolic process [inference]

sphingolipid metabolic process

ceramide metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process

galactosylceramide biosynthetic process

ceramide biosynthetic process [inference]

galactosylceramide biosynthetic process

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process

galactosylceramide biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

ceramide biosynthetic process [inference]

galactosylceramide biosynthetic process

lipid biosynthetic process [inference]

glycolipid biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

ceramide biosynthetic process [inference]

galactosylceramide biosynthetic process

glycerolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process

galactosylceramide biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

glycolipid biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

protein N-linked glycosylation

glycolipid biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

glycosylceramide metabolic process [inference]

galactosylceramide metabolic process

galactosylceramide biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

glycolipid biosynthetic process

glycosphingolipid biosynthetic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

galactolipid metabolic process [inference]

galactosylceramide metabolic process

galactosylceramide biosynthetic process

galactolipid biosynthetic process [inference]

galactosylceramide biosynthetic process

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IEA
plasma membrane	TAS
membrane	TAS
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
galactosylceramide sulfotransferase activity	ISS
galactosylceramide sulfotransferase activity	EXP
galactosylceramide sulfotransferase activity	TAS
galactosylceramide sulfotransferase activity	IDA
galactosylceramide sulfotransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity

galactose 3-O-sulfotransferase activity

galactosylceramide sulfotransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Galactose-3-O-sulfotransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
galactose 3-O-sulfotransferase activity
galactosylceramide sulfotransferase activity
glycolipid biosynthetic process

Displaying **all 2** entries
InterPro
Galactose-3-O-sulfotransferase
P-loop containing nucleoside triphosphate hydrolase

GlycoGene Database (GGDB)

GGDB ID

gg041

Gene Symbol

GAL3ST1

Reactions

Displaying 1 entry
Donor	Acceptor	Reducing terminal(Acceptor)	Reference
PAPS	G65889KE	Ceramide	9030544

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Mus musculus	NP_058618	NM_016922
Rattus norvegicus	AAH87145	BC087145

KEGG BRITE Database

Orthology

K01019

Name

galactosylceramide sulfotransferase [EC:2.8.2.11]

References

Rhea

RHEA:20613

a β-D-galactosyl-(1↔1ʼ)-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate

H⁺ + adenosine 3',5'-bisphosphate + N-acyl-1-β-D-(3-O-sulfo)-galactosyl-sphing-4-enine

Enzyme

2.8.2.11

PMID

RHEA:41744

3'-phosphoadenylyl sulfate + a 1-O-alkyl-2-acyl-3-O-(β-D-galactosyl)-sn-glycerol

H⁺ + adenosine 3',5'-bisphosphate + a 1-O-alkyl-2-acyl-3-(β-D-3-sulfogalactosyl)-sn-glycerol

Enzyme

2.8.2.11

PMID

8830034

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002076
Gene Name: galactose-3-O-sulfotransferase 1

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	53897	MGI:1858277
Rattus norvegicus	683713	RGD:1583379
Danio rerio	793584	ZFIN:ZDB-GENE-091117-38
Danio rerio	793735	ZFIN:ZDB-GENE-060526-375
Xenopus laevis	108715331	Xenbase:XB-GENE-17346330
Xenopus laevis	108707055	Xenbase:XB-GENE-17346331
Xenopus tropicalis	100495120	Xenbase:XB-GENE-984916

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements