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MIRAGE

SEC22 homolog B, vesicle trafficking protein

Summary

Gene Symbol

SEC22B

Organism

Homo sapiens (human)

External Links

NCBI Gene

9554

KEGG Gene ID

PubChem

9554

Alliance of Genome Resources

HGNC:10700

Annotation

Keyword

3D-structure
Acetylation
Coiled coil
Direct protein sequencing
ER-Golgi transport
Endoplasmic reticulum
Golgi apparatus
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O75396	ER-Golgi SNARE of 24 kDa SEC22 vesicle-trafficking protein homolog B SEC22 vesicle-trafficking protein-like 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum to Golgi vesicle-mediated transport	TAS
endoplasmic reticulum to Golgi vesicle-mediated transport	IEA
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IEA
vesicle fusion	NAS
cellular response to starvation	NAS

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

autophagy [inference]

macroautophagy

intercellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle-mediated transport

Golgi vesicle transport [inference]

cellular localization [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

protein transport

vesicle-mediated transport

Golgi vesicle transport [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular localization [inference]

intracellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of cellular process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of autophagy [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of macroautophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular component biogenesis [inference]

regulation of organelle assembly [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

negative regulation of autophagosome assembly

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of autophagy [inference]

negative regulation of macroautophagy [inference]

negative regulation of autophagosome assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of vacuole organization [inference]

regulation of autophagosome assembly [inference]

negative regulation of autophagosome assembly

regulation of organelle assembly [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

regulation of autophagosome assembly [inference]

negative regulation of autophagosome assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of organelle assembly [inference]

negative regulation of autophagosome assembly

Displaying entries **11 - 15** of 21 in total

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GO Term	Evidence Code	PMID
endomembrane system	IEA
ER to Golgi transport vesicle membrane	TAS
ER to Golgi transport vesicle membrane	IDA
membrane	IEA
transport vesicle	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

autophagosome membrane

lytic vacuole membrane [inference]

lysosomal membrane

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

endoplasmic reticulum-Golgi intermediate compartment membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle

pigment granule [inference]

melanosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
SNAP receptor activity	IEA
protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

SNAP receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	20333	MGI:1338759

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Last updated: April 6, 2026