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BCAR1 scaffold protein, Cas family member

Summary

Gene Symbol

BCAR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

9564

KEGG Gene ID

PubChem

9564

Alliance of Genome Resources

HGNC:971

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell adhesion
Cell junction
Cell projection
Cytoplasm
Diabetes mellitus
Direct protein sequencing
Phosphoprotein
Proteomics identification
Reference proteome
SH3 domain
SH3-binding

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P56945	CRK-associated substrate Cas scaffolding protein family member 1 p130cas
B3KWE2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 27 in total

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GO Term	Evidence Code	PMID
regulation of cell growth	TAS
actin filament organization	IDA
cell adhesion	NAS
cell surface receptor protein tyrosine kinase signaling pathway	IBA
cell surface receptor protein tyrosine kinase signaling pathway	IEA

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

cellular process [inference]

cell adhesion

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

insulin receptor signaling pathway

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

integrin-mediated signaling pathway

neurotrophin signaling pathway [inference]

neurotrophin TRK receptor signaling pathway

G protein-coupled receptor signaling pathway

endothelin receptor signaling pathway

cell motility [inference]

cell migration

cell chemotaxis

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

supramolecular fiber organization [inference]

actin filament organization

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

response to hepatocyte growth factor [inference]

cellular response to hepatocyte growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to hepatocyte growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to hepatocyte growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

regulation of growth [inference]

regulation of cell growth

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of endothelial cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of endothelial cell migration

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

insulin receptor signaling pathway

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

integrin-mediated signaling pathway

neurotrophin signaling pathway [inference]

neurotrophin TRK receptor signaling pathway

G protein-coupled receptor signaling pathway

endothelin receptor signaling pathway

regulation of programmed cell death [inference]

regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of endothelial cell migration

regulation of cellular component organization [inference]

regulation of cell growth

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of endothelial cell migration

Displaying entries **11 - 15** of 16 in total

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GO Term	Evidence Code	PMID
focal adhesion	IBA
focal adhesion	IEA
actin cytoskeleton
membrane
lamellipodium

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI
SH3 domain binding
protein kinase binding	IPI

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

protein domain specific binding [inference]

SH3 domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

breast cancer anti-estrogen resistance protein 1

Functional Category

C: Energy production and conversion
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cell migration
transmembrane receptor protein tyrosine kinase signaling pathway

Displaying **all 6** entries
InterPro
CAS family, C-terminal
CAS family
CAS, serine rich four helix bundle domain superfamily
SH3 domain
SH3-like domain superfamily
Serine rich protein interaction domain