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Guidelines
MIRAGE
mediator complex subunit 13
Summary
- Gene Symbol
-
- MED13
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Direct protein sequencing
- Disease variant
- Intellectual disability
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9UHV7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| regulation of transcription by RNA polymerase II |
|
|
| cholesterol homeostasis |
|
|
| positive regulation of DNA-templated transcription |
|
|
| positive regulation of transcription, DNA-templated |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| nucleus |
|
|
| nucleoplasm |
|
|
| nucleoplasm |
|
|
| membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription coregulator activity |
|
|
| transcription coregulator activity |
|
|
| transcription coactivator activity |
|
|
| transcription coactivator activity |
|
|
| transcription coactivator activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- mediator of RNA polymerase II transcription subunit 13
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| MID domain of medPIWI |
| Mediator complex subunit Med13, C-terminal |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060307 | autosomal dominant intellectual developmental disorder |
