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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G49108TO
Summary
- GlyTouCan ID
-
G49108TO
- IUPAC Condensed
- GlcNAc(b1-
3D Structures
- GLYCAM
- DGlcpNAcb1-OH
G14843DJ
G68544GH
Organisms
| Organisms | Evidence |
|---|---|
| Mus musculus (house mouse) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) | |
| Drosophila melanogaster (fruit fly) | |
| Streptococcus pneumoniae |
Taxonomic Hierarchy
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B3GALT1 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALNT3 | UDP-GalNAc |
G49108TO
|
R |
G00057MO
|
R | |
| B3GALNT2 | UDP-GalNAc |
G49108TO
|
R |
G36387CV
|
R | |
| B4GALNT4 | UDP-GalNAc |
G49108TO
|
R |
G00057MO
|
R | |
| B4GALT1 | UDP-Glc |
G49108TO
|
R |
G38884XS
|
R |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| B4GALT5 | (not applicable) |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| B4GALT3 | UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-Benzl |
G00055MO
|
[beta]-1-Benzl | |
| B3GALT2 | UDP-Gal |
G49108TO
|
Lemieux |
G00056MO
|
Lemieux | |
| B4GALT4 | UDP-Gal |
G49108TO
|
[beta]-1-4-methyl-umbelliferyl |
G00055MO
|
[beta]-1-4-methyl-umbelliferyl |
Core Protein
GlycoEpitope
- Epitope ID
- EP0004
Pathway
| Pathway Name | Organism |
|---|---|
| Lectin pathway of complement activation | Rattus norvegicus |
| Lectin pathway of complement activation | Homo sapiens |
| Lectin pathway of complement activation | Canis familiaris |
| Lectin pathway of complement activation | Sus scrofa |
| Lectin pathway of complement activation | Bos taurus |
| Lectin pathway of complement activation | Mus musculus |
| Lectin pathway of complement activation | Gallus gallus |
Sequence Descriptors
- GlycoCT
-
RES 1b:b-dglc-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2122h-1b_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 36877249 | Crystal structure and identification of amino acid residues for catalysis and binding of GH3 AnBX β-xylosidase from Aspergillus niger | Kaenying W | 2023 Mar 06 |
|
| 36861967 | Author response: O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors | Zhang Z | 2023 Mar 02 |
|
| 36752318 | Design of OSMI‐4 Analogs Using Scaffold Hopping: Investigating the Importance of the Uridine Mimic in the Binding of OGT Inhibitors | Balsollier C | 2023 Mar 02 |
|
| 36736606 | Evidence that only EWS among the FET proteins acquires a low partitioning property for the hyperosmotic stress response by O-GlcNAc glycosylation on its low-complexity domain | Kakuo M | 2023 Mar 01 |
|
| 36427797 | Structure of human placental steroid sulfatase at 2.0 angstrom resolution: Catalysis, quaternary association, and a secondary ligand site | Ghosh D | 2023 Mar |
|
| 36916782 | Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS‐CoV‐2 | Kwon HJ | 2023 Mar |
|
| 37086786 | O-GlcNAcylation promotes the cytosolic localization of the m6A reader YTHDF1 and colorectal cancer tumorigenesis | Li J | 2023 Jun |
|
| 37384723 | Variability in phenylalanine side chain conformations facilitates broad substrate tolerance of fatty acid binding in cockroach milk proteins | Santhakumari PR | 2023 Jun 29 |
|
| 37339051 | A structural blueprint for interleukin-21 signal modulation | Abhiraman GC | 2023 Jun 27 |
|
| 37425865 | Focusing antibody responses to the fusion peptide in rhesus macaques | Cottrell CA | 2023 Jun 27 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. |
|
J Am Chem Soc | 2003 Jun 4 | 12769553 |
| Effect of okadaic acid on O-linked N-acetylglucosamine levels in a neuroblastoma cell line. |
|
Biochim Biophys Acta | 1999 Oct 18 | 10572927 |
| Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. |
|
J Biol Chem | 1999 Nov 5 | 10542233 |
| An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. |
|
J Biol Chem | 1999 May 21 | 10329728 |
| Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. |
|
J Biol Chem | 1992 Jan 5 | 1730617 |
