G90387AM

Summary
GlyTouCan ID
G90387AM
IUPAC Condensed
Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(?1-
Motifs
3-Sialyl-LN (type 2) Lewis x Lex SSEA-1
Subsumption Level
Linkage-defined saccharide
Monoisotopic Mass
820.3
GlyGen
ChEBI
PubChem Compound
PubChem Substance
CarbBank
46377 46708
3D Structures
GlycoShape
KEGG BRITE Database
KEGG ID
References
Pathway
Displaying entries 1 - 10 of 12 in total
Pathway Name Organism
Lewis blood group biosynthesis Rattus norvegicus
Lewis blood group biosynthesis Sus scrofa
Lewis blood group biosynthesis Canis familiaris
Lewis blood group biosynthesis Drosophila melanogaster
Lewis blood group biosynthesis Bos taurus
Lewis blood group biosynthesis Mus musculus
Lewis blood group biosynthesis Caenorhabditis elegans
Lewis blood group biosynthesis Homo sapiens
Lewis blood group biosynthesis Xenopus tropicalis
Lewis blood group biosynthesis Gallus gallus
Sequence Descriptors
GlycoCT
RES
1b:x-dglc-HEX-1:5
2s:n-acetyl
3b:a-lgal-HEX-1:5|6:d
4b:b-dgal-HEX-1:5
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d
4:4o(3+2)5d
5:5d(5+1)6n
WURCS
WURCS=2.0/4,4,3/[a2122h-1x_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-4/a3-b1_a4-c1_c3-d2
Literature
Displaying entries 11 - 20 of 1046 in total
PubMed ID Title First Author Publication Date Source
38197965 Altered expression of Sialyl Lewis X in experimental models of Parkinson’s disease Nunes MJ 2024 Jan 10
  • PubChem
38387051 Prevention of experimental autoimmune encephalomyelitis by targeting 6-sulfo sialyl Lewis X glycans involved in lymphocyte homing Liu Q 2024 Feb 22
  • PubChem
38340724 Merkel cell polyomavirus-specific and CD39+CLA+ CD8 T cells as blood-based predictive biomarkers for PD-1 blockade in Merkel cell carcinoma Ryu H 2024 Feb 20
  • PubChem
38064497 Prevention of Collagen-Induced Arthritis by an Anti-Glycan Monoclonal Antibody Reactive with 6-Sulfo Sialyl Lewis x in DBA/1 Mice Wei Z 2024 Feb 01
  • PubChem
38348177 Precision USPIO-PEG-SLex Nanotheranostic Agent Targeted Photothermal Therapy for Enhanced Anti-PD-L1 Immunotherapy to Treat Immunotherapy Resistance Li T 2024 Feb
  • PubChem
38659295 Combining 5‐azacitidine with the E‐selectin antagonist uproleselan is an effective strategy to augment responses in myelodysplasia and acute myeloid leukaemia Enjeti AK 2024 Apr 24
  • PubChem
38639586 Sialyl Lewis X Defines an Activated and Functional Regulatory T Cell Subpopulation in Mice Ohishi K 2024 Apr 19
  • PubChem
38578028 Let's Get Rolling: Precise Control of Microfluidic Assay Conditions to Recapitulate Selectin‐Mediated Rolling Interactions of the Leukocyte Adhesion Cascade Amoabediny Z 2024 Apr
  • PubChem
37735247 A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses Liu W 2023 Sep 21
  • PubChem
36985569 A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics Wagner B 2023 Mar 13
  • PubChem

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025