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Anoctamin-9

Summary

UniProt ID: A1A5B4
Gene Symbol: ANO9 PIG5 TMEM16J TP53I5
Gene ID: 338440
Organism: Homo sapiens (human)

External Links

GlyGen: A1A5B4
PubChem: A1A5B4
The Human Metabolome Database: HMDBP07447
Re-Glyco: A1A5B4

Annotation

Keyword: Alternative splicing Cell membrane Endoplasmic reticulum Glycoprotein Lipid metabolism Lipid transport Phosphoprotein Proteomics identification Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
lipid metabolic process
sensory perception of smell	IEA	GO_REF
ion transmembrane transport	TAS	Reactome
monoatomic ion transmembrane transport	TAS	Reactome
establishment of localization in cell

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of smell

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

lipid transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

organophosphate ester transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

establishment of localization in cell

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
endoplasmic reticulum	IDA	PMID
endoplasmic reticulum	IEA	GO_REF GO_REF
plasma membrane	EXP	PMID
plasma membrane	TAS	Reactome
plasma membrane	IDA	PMID PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
intracellularly calcium-gated chloride channel activity	IDA	PMID PMID
intracellularly calcium-gated chloride channel activity	IMP	PMID
chloride channel activity	TAS	Reactome
chloride channel activity	IEA	GO_REF
calcium channel activity	IMP	PMID

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

monoatomic cation channel activity [inference]

calcium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellularly calcium-gated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellularly calcium-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

monoatomic cation channel activity [inference]

calcium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

intracellularly calcium-gated chloride channel activity

intracellularly calcium-gated channel activity [inference]

intracellularly calcium-gated chloride channel activity

intramembrane lipid carrier activity [inference]

phospholipid scramblase activity

binding [inference]

protein binding [inference]

protein dimerization activity

molecular function regulator activity [inference]

molecular function inhibitor activity [inference]

transporter inhibitor activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

chloride channel inhibitor activity

transporter regulator activity [inference]

channel regulator activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

chloride channel inhibitor activity

ion channel regulator activity [inference]

ion channel inhibitor activity [inference]

chloride channel inhibitor activity

chloride channel regulator activity [inference]

chloride channel inhibitor activity

transporter inhibitor activity [inference]

channel inhibitor activity [inference]

ion channel inhibitor activity [inference]

chloride channel inhibitor activity

molecular carrier activity [inference]

lipid carrier activity [inference]

intramembrane lipid carrier activity [inference]

phospholipid scramblase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MQGEESLRILVEPEGDSFPLMEISTCETEASEQWDYVLVAQRHTQRDPRQARQQQFLEELRRKGFHIKVIRDQKQVFFGIRADNSVFGLYRTLLLEPEGPAPHAELAAPTTIPVTTSLRIRIVNFVVMNNKTSAGETFEDLMKDGVFEARFPLHKGEGRLKKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPPMPAHPTPASIFSARSTDV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
641	N-linked (GlcNAc...) asparagine	24190977 37074911	G62765YT	UniProt GlyGen
652	N-linked (GlcNAc...) asparagine	24190977		UniProt GlyGen
674	N-linked (GlcNAc...) asparagine			UniProt GlyGen
690	N-linked (GlcNAc...) asparagine			UniProt GlyGen
770				GlyGen