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Anoctamin-3

Summary

UniProt ID: A2AHL1
Gene Symbol: Ano3 Tmem16c
Gene ID: 228432
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0001651

PubChem

A2AHL1

SwissLipids

SLP:000000377

Re-Glyco

A2AHL1

Annotation

Keyword: Alternative splicing Cell membrane Glycoprotein Lipid transport Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	Reference
detection of temperature stimulus	ISO	GO_REF
detection of temperature stimulus	IEA	GO_REF
detection of mechanical stimulus	ISO	GO_REF
detection of mechanical stimulus	IEA	GO_REF
calcium activated phosphatidylcholine scrambling	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

response to mechanical stimulus [inference]

detection of mechanical stimulus

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus

detection of abiotic stimulus [inference]

response to mechanical stimulus [inference]

detection of mechanical stimulus

detection of stimulus [inference]

detection of external stimulus [inference]

detection of abiotic stimulus [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

lipid transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

organophosphate ester transport [inference]

phospholipid transport [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation [inference]

plasma membrane phospholipid scrambling [inference]

calcium activated phospholipid scrambling [inference]

Displaying **all 2** entries
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	Reference
chloride channel activity
phospholipid scramblase activity	IDA	PMID
phospholipid scramblase activity	IBA	GO_REF
protein dimerization activity	IEA	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intramembrane lipid carrier activity [inference]

phospholipid scramblase activity

binding [inference]

protein binding [inference]

protein dimerization activity

molecular carrier activity [inference]

lipid carrier activity [inference]

intramembrane lipid carrier activity [inference]

phospholipid scramblase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MVHHSGSIQSFKQQKGMNISKSEITTEASLKPSRRSLPCLAQSYAHSKSLSQSASLFQSTESESQAPTSVTFLSADKPEHVTSEESRKDSTLKCSFADLSDFCLALGKDKDYLDESEHANYDRSRLLNDFVTKDKPASKTKLSKNDMSYIASSGLLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIANPDIMFIKIHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSKSRVQNYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLITNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRMYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNESQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYRMEVINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFVKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDASIPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQRRKSGQPIHHEWP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
425	N-linked (GlcNAc...) asparagine	UniProt
448	N-linked (GlcNAc...) asparagine	UniProt
455	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
866	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Stimuli-sensing channels	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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