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Rap1 GTPase-activating protein 1

Summary

UniProt ID: A2ALS5
Gene Symbol: Rap1gap Kiaa0474 Rap1ga1
Gene ID: 110351
Organism: Mus musculus (house mouse)

External Links

GlyGen: A2ALS5
PubChem: A2ALS5
The O-GlcNAc Database: A2ALS5
O-GlcNAcAtlas: A2ALS5
Re-Glyco: A2ALS5

Annotation

Keyword: Alternative splicing GTPase activation Golgi apparatus Membrane Phosphoprotein Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
positive regulation of cell-cell adhesion	IMP	PMID
negative regulation of neuron differentiation	ISO	GO_REF
negative regulation of neuron differentiation	IEA	GO_REF
positive regulation of phagocytosis	IMP	PMID
regulation of small GTPase mediated signal transduction	IEA	GO_REF

GO Hierarchy

biological process

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to glial cell derived neurotrophic factor

response to glial cell derived neurotrophic factor [inference]

cellular response to glial cell derived neurotrophic factor

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to glial cell derived neurotrophic factor

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of thyroid gland epithelial cell proliferation

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of thyroid gland epithelial cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of thyroid gland epithelial cell proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of thyroid gland epithelial cell proliferation

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of thyroid gland epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of thyroid gland epithelial cell proliferation

regulation of thyroid gland epithelial cell proliferation [inference]

negative regulation of thyroid gland epithelial cell proliferation

regulation of cellular component biogenesis [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of microvillus assembly [inference]

negative regulation of microvillus assembly

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of thyroid gland epithelial cell proliferation

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of microvillus assembly [inference]

negative regulation of microvillus assembly

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of microvillus organization [inference]

regulation of microvillus assembly [inference]

negative regulation of microvillus assembly

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of microvillus assembly [inference]

negative regulation of microvillus assembly

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of plasma membrane bounded cell projection assembly [inference]

negative regulation of microvillus assembly

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of thyroid gland epithelial cell proliferation

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
Golgi membrane	IEA	GO_REF
cytoplasm
early endosome	ISO	GO_REF
early endosome	IEA	GO_REF
cytosol	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
GTPase activator activity	ISO	GO_REF
GTPase activator activity	IBA	GO_REF
GTPase activator activity	IEA	GO_REF GO_REF
small GTPase binding	ISO	GO_REF
small GTPase binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTNHEISSLPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTHHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFTPNNPDLAKAAGISLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRVESAAQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGLESVSSSGTPHKRDSFLYSTWLDDSVSTTSGGSSPGLTRSPHPDVGKSGDPACPEIKIQLETSEQHTPQMGC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	PubMed ID	GlyTouCan ID	Source
458	22645316 33300544 40885482	G49108TO	GlyGen The O-GlcNAc Database
460	22645316 33300544 40885482	G49108TO	The O-GlcNAc Database
464	22645316 33300544 40885482	G49108TO	The O-GlcNAc Database