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Zinc metalloproteinase-disintegrin-like VAP2A

Summary

UniProt ID: A4PBQ9
Organism: Crotalus atrox (western diamondback rattlesnake)

External Links

Re-Glyco: A4PBQ9

Annotation

Keyword: Calcium Direct protein sequencing Disulfide bond Glycoprotein Hemorrhagic toxin Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Pyrrolidone carboxylic acid Secreted Signal Zinc

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
proteolysis	IEA	GO_REF
venom-mediated hemorrhage	IDA	PMID
venom-mediated suppression of platelet aggregation	IDA	PMID
venom-mediated disruption of extracellular matrix in another organism	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

venom-mediated perturbation of biological process [inference]

venom-mediated perturbation of blood circulation [inference]

venom-mediated perturbation of hemostasis [inference]

disruption of anatomical structure in another organism [inference]

venom-mediated disruption of anatomical structure in another organism [inference]

venom-mediated disruption of extracellular matrix in another organism

Displaying **all 3** entries
GO Term	Evidence Code	Reference
extracellular region	EXP	PMID PMID
extracellular region	IEA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	IEA	GO_REF
metallopeptidase activity	IDA	PMID
metallopeptidase activity	IEA	GO_REF
metal ion binding
toxin activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

toxin activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MIQVLLVTICLAAFPYQGSSIILESGNVNDYEIVYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLEKNKQLFSKDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTQNWKSYEPIKKASQLVVTAEHQKYNPFRFVELVLVVDKAMVTKNNGDLDKIKTRMYELANTVNDIYRYMYIHVALVGLEIWSNEDKITVKPEADYTLNAFGEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSPINLVVAVIMAHEMGHNLGINHDRGYCSCGDYACIMRPEISPEPSTFFSNCSYFDCWDFITNHNPECIVNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNSCKMFYSNEDEHKGMVLPGTKCADGKVCSNGHCVDVATAY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites