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Eukaryotic translation initiation factor 4G1, isoform B

Summary

UniProt ID: A8DZ29
Gene Symbol: CG10811 Dmel\CG10811 Dmel_CG10811 EIF4G EIF4G1 Eif4G deIF4G eIF-4G eIF4G eIF4G1 eIF4g eiF-4G p200
Gene ID: 43839
Organism: Drosophila melanogaster (fruit fly)

External Links

GlyGen: A8DZ29
The O-GlcNAc Database: A8DZ29
Re-Glyco: A8DZ29

Annotation

Keyword: Initiation factor Phosphoprotein Proteomics identification Reference proteome Translation regulation

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
mitotic cell cycle	HMP	PMID
translation	IDA	PMID
translational initiation	ISS	PMID
translational initiation	IBA	GO_REF
regulation of translation	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell cycle [inference]

mitotic cell cycle

metabolic process [inference]

translational initiation

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translation

protein metabolic process [inference]

translation

primary metabolic process [inference]

protein metabolic process [inference]

translation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of protein metabolic process [inference]

regulation of translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation

Displaying **all 3** entries
GO Term	Evidence Code	Reference
cytosol	HDA	PMID
eukaryotic translation initiation factor 4F complex	IDA	PMID PMID
eukaryotic translation initiation factor 4F complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

RNA cap binding complex [inference]

eukaryotic translation initiation factor 4F complex

cellular anatomical structure [inference]

cytosol

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
RNA 7-methylguanosine cap binding	IDA	PMID
RNA binding	IDA	PMID
RNA binding	IEA	GO_REF
mRNA binding
translation initiation factor activity	ISS	GO_REF

GO Hierarchy

molecular function

binding [inference]

nucleic acid binding [inference]

RNA binding

RNA cap binding [inference]

RNA 7-methylguanosine cap binding

mRNA binding

protein binding [inference]

translation initiation factor binding [inference]

eukaryotic initiation factor 4E binding

translation factor activity [inference]

translation initiation factor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MQQAIPTLPTQSDIDKAMQPHSAQNMILPANKKTKKYDQQVPTSKPQSLHQPLQPQHSHPTAQPQFQINKAYNVVSILKASAQIAQQSPHLTNQQHPPIHHPQQTQQHQQSYTNVVNRSLSASEPVRAQSSVICNGSSILTVNSRQLNSGDMNSTAIYNISSYRKLTGSLDGNVCFLNVQDIKQNGNISGSVVSNKSIVGVGSEKSSCTGVSINNQIVLPNAQIGTSMGIAGTTTAGTSYMHEKNIVGVSVNCVNTSKKYDFNNSSLLSNNSYPASTAEYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPNGPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVSAMTDAPSVEILPTPQRGRSKKIPIVSPKNVSESIVAPITDETDDAGSTPISRATEESMPPNQTHPNLLISDSSKHKQAVSNSEISKDAPTGLKEMHVAELESSVASENHPAGILDVNVNKSSQSLDFSADPEIDSIGAISPTSPNAVSPILHEVLDNTELSKKLENSTTERFKDSQSVEKPTHQELSLRNATDETEISAMALQDVNSLDNNQIEKTYPSKPKLNVDVSEDISSRESAIKSTSTKNTGVDVGLQSDSKPETTLNDKQDSTDLKVKVSAKISSIINYNEGQWSPNNPSGKKQYDREQLLQLREVKASRIQPEVKNVSILPQPNLMPSFIRNNNNNKRVQSMVGIIGNRSNESAGNYIGKQMSMSGVQSGGGRSSMKGMIHVNLSLNQDVKLSENENAWRPRVLNKSDGDSDAKSALEKDELVRRVRGILNKLTPERFDTLVEEIIKLKIDTPDKVDEVIVLVFEKAIDEPNFSVSYARLCQRLAAEVKVIDERMESETKSNSAHFRNALLDKTEQEFTQNVSQSTAKEKKLQPIVDKIKKCTDANEKAELEAFLEEEERKIRRRSGGTVRFIGELFKISMLTGKIIYSCIDTLLNPHSEDMLECLCKLLTTVGAKFEKTPVNSKDPSRCYSLEKSITRMQAIASKTDKDGARVSSRVRFMLQDVIDLRKNKWQTSRNEAPKTMGQIEKEAKNEQLSAQYFGTLSSTTPGGSQGGSGKRDDRGNSRYGESRSSSAYGGSHSQRGDNGNLRHQQQNNVGGNVSGGAGHSNGNNDENTWHVQTSKGSRSLAVDSNKLEGLSKLSDQNLETKKMGGLTQFIWISSDTTRLSSAPTPTPSNPFAVLSSLIDKNSNERDRDRSGPRNKGSYNKGSMERDRYDRGMHSRTGSSQGSRENSSSRGGQQGRTLLSSSVQKSTSHSKYTQQAPPTRHTVKAQSSVGSSNVNTGPLYRGSEQQTSATFSQTTRSVAPVAVFIEASETDLKLIKSVVSEIVDLSAASKEVTPGAVSCIKRVPEKLRCSFIYYILTDYLHLANVGKQYRRYLSIAVSQLIQQNYISADHLRLAYNEFTVYANDLIVDIPELWLYILQFAGPLIVKKILTISDLWNNNLKENSPSNVAKKFLKTYLIYCTQEVGPNFARNMWIKFNLKWSDFMPESEVADFIKFNRLEYVENESKSPVIDHRETPEKHVKNVIDHIEHLLKEGTTADCIIDYSNGNIMVVDKLFIRGLTETLSNFSIHYKDNSYKLESETFQKFCIPVLQRYIDSNEDHQLECLYTLQLLVHGLEHPRGLLSELIGELYDAFVIQKESLCKWRDSKDQSAGKGVAVKSLNPFFNSLLNDDAN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	PubMed ID	GlyTouCan ID	Source
539	40245499	G49108TO	The O-GlcNAc Database
562	40245499	G49108TO	The O-GlcNAc Database
564	40245499	G49108TO	The O-GlcNAc Database
569			GlyGen
586			GlyGen
624	40245499	G49108TO	The O-GlcNAc Database
715			GlyGen
1412			GlyGen
1414			GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
AUF1 (hnRNP D0) binds and destabilizes mRNA	Drosophila melanogaster
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	Drosophila melanogaster
Deadenylation of mRNA	Drosophila melanogaster
L13a-mediated translational silencing of Ceruloplasmin expression	Drosophila melanogaster
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Drosophila melanogaster
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Drosophila melanogaster
Ribosomal scanning and start codon recognition	Drosophila melanogaster
Translation initiation complex formation	Drosophila melanogaster
mTORC1-mediated signalling	Drosophila melanogaster

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements