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Melanocortin receptor 4

Summary

UniProt ID

B0V1P1

Gene Symbol

mc4r

Gene ID

[286833]

Organism

Danio rerio (zebrafish)

External Links

Re-Glyco: B0V1P1

Annotation

Keyword: Calcium Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Metal-binding Palmitate Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
energy reserve metabolic process	IDA	PMID
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	PMID
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	GO_REF
regulation of growth	IGI	PMID PMID
regulation of feeding behavior	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of growth

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of behavior [inference]

negative regulation of feeding behavior

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

negative regulation of behavior [inference]

negative regulation of feeding behavior

regulation of feeding behavior

negative regulation of feeding behavior

negative regulation of multicellular organismal process [inference]

negative regulation of behavior [inference]

negative regulation of feeding behavior

Displaying **all 4** entries
GO Term	Evidence Code	Reference
cytoplasm	IBA	GO_REF
plasma membrane	ISS	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
melanocortin receptor activity	IDA	PMID
melanocortin receptor activity	IEA	GO_REF GO_REF
melanocyte-stimulating hormone receptor activity	IBA	GO_REF

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

melanocortin receptor activity

melanocyte-stimulating hormone receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

melanocortin receptor activity

melanocyte-stimulating hormone receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNTSHHHGLHHSFRNHSQGALPVGKPSHGDRGSASGCYEQLLISTEIFLTLGLVSLLENILVIAAIVKNKNLHSPMYFFICSLAVADLLVSVSNASETVVMALITGGNLTNRESIIKNMDNVFDSMICSSLLASIWSLLAIAVDRYITIFYALRYHNIMTQRRAGTIITCIWTFCTVSGVLFIVYSESTTVLICLISMFFTMLALMASLYVHMFLLARLHMKRIAALPGNGPIWQAANMKGAITITILLGVFVVCWAPFFLHLILMISCPRNPYCVCFMSHFNMYLILIMCNSVIDPLIYAFRSQEMRKTFKEICCCWYGLASLCV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
2	N-linked (GlcNAc...) asparagine	UniProt
15	N-linked (GlcNAc...) asparagine	UniProt
94	N-linked (GlcNAc...) asparagine	UniProt
108	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Peptide ligand-binding receptors	Danio rerio

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements