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A disintegrin and metalloproteinase with thrombospondin motifs 1

Summary

UniProt ID: B2GUP2
Gene Symbol: adamts1 c3-c5 meth1 xadamts1
Gene ID: 100151734
Organism: Xenopus tropicalis (tropical clawed frog)

External Links

Re-Glyco: B2GUP2

Annotation

Keyword: Calcium Cleavage on pair of basic residues Disulfide bond Extracellular matrix Glycoprotein Heparin-binding Metal-binding Metalloprotease Reference proteome Repeat Signal Zinc Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
proteolysis	IBA	GO_REF
proteolysis	IEA	GO_REF
extracellular matrix organization	IBA	GO_REF
extracellular matrix organization	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

Displaying **all 2** entries
GO Term	Evidence Code	Reference
extracellular matrix	IBA	GO_REF
extracellular matrix	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

external encapsulating structure [inference]

extracellular matrix

Displaying **all 4** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	IBA	GO_REF
metalloendopeptidase activity	IEA	GO_REF
heparin binding
zinc ion binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MMGYLLPWMAALLCARNALGMGTALEEELVAPVRLDPGTAQGESGNGKVRYHLNVFGESLTLDLEPDRTFLAPDFSLQYVGSPAERNGGAEPLAELAKCFYSGSVNGDSTSSAALSLCSGLRGAFFYRGEEYLIQPSNHTLTVADPDSPDPLVLHLVRRRSRAKAKCGVTDSVGQPVKSEDAPSQRTMPPTGSGSSRRKKRFVSSPRYVETMLVADQSMAEFHGSSLKHYLLTLMSVAAKLYKHPSIRNSISIVVVKILVIYDEQKGPDVSSNAALTLRNFCSWQKQHNPPSDRHAEHYDTAILFTRQDLCGAQTCDTLGMADVGTICDPTRSCSIIEDDGLQAAFTTAHELGHVFNMPHDEAKQCSGLNRDNQDSHMMASMLSNLDRYEPWSPCSAYMITSFLDNGHGECLLDKPHRPIQLPSDLPGTLYDANKQCQFTFGDESRHCPDAASTCTTLWCTGVSGGLLVCQTKHFPWADGTSCGEGKWCINGKCMDQTDKKHYETPVHGGWGAWGQWGECSRTCDGGVQYSVRECDNPVPKNGGKYCEGKRVQYRSCNIQDCPENNGKTYREEQCEAHNDLSKSPFGSGPAVEWTPKYAGVSPKDRCKLMCRAKGTGYFFVLNPKVVDGTPCSPDSTSMCIQGQCVKAGCDRVIGSSKKFDKCGVCGGNGSTCKKVSGNFIISRPGYQDVVTIPAGATNIEVKQRNNRGSRHDGSFLAIKAADGNYILNGDYTLSTLEQDIIHNGNILRYSGSSASLERIRSFSPLKEPITIQVLTVGDSHRLKIKYVYFVKKTGQPEKPNKKKESFNAIRETILSEWVIEEWGECSKTCGLGWQRRTVECKDINGQPSTDCANELKPDDIRPCADTPCPQWQLGDWSSCSKTCGKGFKKRLLKCVSYDGVSMPQENCDPLKKPKHLIDFCTLANCS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
669	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
O-glycosylation of TSR domain-containing proteins	Xenopus tropicalis

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements