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Multimerin-1

Summary

UniProt ID: B2RPV6
Gene Symbol: Mmrn1
Gene ID: 70945
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0001908
RaftProt: B2RPV6
Re-Glyco: B2RPV6

Annotation

Keyword: Alternative splicing Coiled coil Disulfide bond EGF-like domain Glycoprotein Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
negative regulation of vascular endothelial growth factor receptor signaling pathway	IBA	GO_REF
cell adhesion mediated by integrin	ISO	GO_REF
negative regulation of wound healing	ISO	GO_REF
negative regulation of wound healing	IDA	PMID
negative regulation of wound healing	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell adhesion mediated by integrin

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of blood vessel endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of cell migration involved in sprouting angiogenesis [inference]

negative regulation of cell migration involved in sprouting angiogenesis

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of wound healing

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of response to wounding [inference]

negative regulation of wound healing

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of wound healing

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of wound healing

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of response to wounding [inference]

negative regulation of wound healing

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

negative regulation of wound healing

negative regulation of response to wounding [inference]

negative regulation of wound healing

regulation of cellular response to growth factor stimulus [inference]

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of homotypic cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of vascular endothelial growth factor receptor signaling pathway

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of cell activation [inference]

regulation of platelet activation [inference]

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of endothelial cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of blood vessel endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of cell migration involved in sprouting angiogenesis [inference]

negative regulation of cell migration involved in sprouting angiogenesis

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

negative regulation of cell motility [inference]

negative regulation of cell migration [inference]

negative regulation of endothelial cell migration [inference]

negative regulation of blood vessel endothelial cell migration [inference]

negative regulation of cell migration involved in sprouting angiogenesis

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of platelet activation [inference]

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
extracellular region	ISS	GO_REF
extracellular region	ISO	GO_REF
extracellular region	IEA	GO_REF
extracellular matrix	ISO	GO_REF
extracellular matrix	HDA	PMID PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

protein complex involved in cell adhesion [inference]

protein complex involved in cell-matrix adhesion [inference]

multimerin complex

extracellular protein-containing complex [inference]

multimerin complex

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

Displaying 1 entry
GO Term	Evidence Code	Reference
calcium ion binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLGLKFLVLLSILWGRVFRLTNTQHSWTAPKDEDASLTPNHASASVSEILSLQVLSATQNPSTQGPAAAERSSEDDVLLQSTSQPSETSTPPEGRHQTPLEKTGTAVVSLPLSLQDKPSIKPSTGAGTVMLANATLKFLQSFSRKSDQQEVSTKSAGDMGNRSARETHLRRSDNSRNQRPSYQKPSFETTRGKNWCAHVHTKLSPTVILDTGSHLPSGRGSCGWYSSGLCSRRSQKTSNAVYRMQHKIVTSLEWRCCPGYIGPNCQLKVEEQQQLAHSNQAESHTAVDQGRAQQQKQDCGDPAMIQKLAEQLSQQERKLSLLQKKVDNASLVADDMRNAYLSLEGKVGEDNSRQFQSFLKALKSKSIEDLLKNIVKEQFKVFQDDMQETTAQIFKTVSSLSEDLESTRQAVLQVNQSFVSSTAQKDFAFMQENQPTWKDITDLKNSIMNIRQEMALTCEKPVKELEAKQAHLEGALRQEHSQIVLYHQSLNETLSKMQEAHIQLLSVLQVSGTENVATEESLNSNVTKYISVLQETASKQGLMLLQMLSDLHVQESKISNLTILLEMEKESARGECEEMLSKCRHDFKFQLKDTEENLHVLNQTLSEVIFPMDIKVDKMSEQLNDLTYDMEILQPLLEQRSSLQHQVIHKPKEATVTRRELQNLIGAINQLNVLTKELTKRHNLLRNEVQSRGEAFERRISEHALETEDGLNKTMTVINNAIDFVQDNYVLKETLSAMTYNPKVCECNQNMDNILTFVSEFQHLNDSIQTLVNNKEKYNFILQIAKALTAIPKDEKLNQLNFQNIYQLFNETTSQVNKCQQNMSHLEENMLSVTKTAKEFETRLQGIESKVTKTLIPYYISFKKGGILSNERDVDLQLKVLNTRFKALEAKSIHLSVSFSLLNKTVRELSMACRNASTGTCGQNALIPRWTKGSLPGSQSSQKSLTELVESIVEIKTQAALSNLTWNVDRLLSDTLANIVKPQKQIKLQKKPNTLKKTVNMTTILIGRTQRNTDTIIHPVAQEHSSCSSFPCQNGGTCISGRSNFICACRHPFMGDTCTVKIKEDDAVAPDFSKGSYRYAPMVAFFVSHTHGMTAPGPILFNDLSVNYGASYNPRTGKFRIPYLGVYIFKYTIESFSAHISGFFVVDGVDKLRFESENADNEIHCDRVLTGDALFELNYGQEVWLRLVKGTIPIKYPPVTTFSGYLLYRT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 19 in total

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Position	Description	Source
133	N-linked (GlcNAc...) asparagine	UniProt
161	N-linked (GlcNAc...) asparagine	UniProt
201	O-linked (Fuc) threonine	UniProt
250	O-linked (Fuc) threonine	UniProt
328	N-linked (GlcNAc...) asparagine	UniProt
415	N-linked (GlcNAc...) asparagine	UniProt
491	N-linked (GlcNAc...) asparagine	UniProt
525	N-linked (GlcNAc...) asparagine	UniProt
560	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
602	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
O-linked glycosylation	Mus musculus
Platelet degranulation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements