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G-protein coupled receptor 161

Summary

UniProt ID

B3DM66

Gene Symbol

gpr161

Gene ID

100170613

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

PubChem: B3DM66
Re-Glyco: B3DM66

Annotation

Keyword: Cell membrane Cilium Developmental protein Disulfide bond G-protein coupled receptor Glycoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
G protein-coupled receptor signaling pathway	IEA	GO_REF
adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISS	GO_REF
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	GO_REF
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Displaying **all 4** entries
GO Term	Evidence Code	Reference
cilium
recycling endosome	ISS	GO_REF
recycling endosome	IBA	GO_REF
ciliary membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

Displaying **all 3** entries
GO Term	Evidence Code	Reference
G protein-coupled receptor activity	ISS	GO_REF
G protein-coupled receptor activity	IBA	GO_REF
G protein-coupled receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNSSSDGANEGAGAAADNGPTKVAESIAIIIIDILICLGNLVIVVTLYKKSYLLSLSNKFVFSLTFSNLLLSMLVLPFVVVSSILREWIFGVVWCNFSALLYMLISSASMLTLGIIAIDRYYAVLYPMVYPMKITGNRAVLALVYVWLHSLIGCLPPLFGWSTLEFDHFKWMCVAAWHKEAGYTAFWQVWCALLPFIVMMICYGFIFRVARIKARKIHCGTVIIVQEASQKNGRKNSSTSTSSSGSRKNGFSSIVYSANQCKALITILVVIGAFVLTWGPYMIVISTEALKGKNSVSPVLETLATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGNRYRDPFHQQHRTSRMFSISNRITDLGLSPHLTALMARGTESEHQSTTTNTGFSCSNESGTDVMLLDDTSSDATQLHRVIYSRRKSSVTFEDEVEQKNDARTMPTQPTAPSESLESYAFNLAKAIEMDAKISLFGEDVFPSNVQALPGNSGINRNRINFIQKQRVQLQSIEEGNIETSKCDV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
2	N-linked (GlcNAc...) asparagine			UniProt
96	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Hedgehog 'off' state	Xenopus tropicalis
Hedgehog 'on' state	Xenopus tropicalis

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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