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Cationic amino acid transporter 2

Summary

UniProt ID: B5D5N9
Gene Symbol: Slc7a2 Atrc2 Cat2
Gene ID: 64554
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: B5D5N9

Annotation

Keyword: Alternative splicing Amino-acid transport Cell membrane Glycoprotein Phosphoprotein Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	Reference
nitric oxide production involved in inflammatory response	ISO	GO_REF
nitric oxide biosynthetic process	ISO	GO_REF
L-amino acid transport	ISO	GO_REF
macrophage activation	ISO	GO_REF
regulation of macrophage activation	ISO	GO_REF

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

metabolic process [inference]

biosynthetic process [inference]

nitric oxide biosynthetic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process [inference]

nitric oxide biosynthetic process

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

production of molecular mediator involved in inflammatory response [inference]

nitric oxide production involved in inflammatory response

localization [inference]

establishment of localization [inference]

transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

organic cation transport [inference]

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-arginine import across plasma membrane

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

organic anion transport [inference]

carboxylic acid transport [inference]

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane

carboxylic acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

nitrogen compound transport [inference]

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-alpha-amino acid transmembrane transport

L-arginine import across plasma membrane

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

L-lysine transmembrane transport [inference]

L-lysine import across plasma membrane

L-arginine transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

L-ornithine import across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

regulation of cellular process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

regulation of macrophage activation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	GO_REF
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF
membrane	ISO	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

cell junction

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
L-ornithine transmembrane transporter activity	ISO	GO_REF
L-ornithine transmembrane transporter activity	IBA	GO_REF
high-affinity L-arginine transmembrane transporter activity	ISO	GO_REF
high-affinity lysine transmembrane transporter activity	ISO	GO_REF
amino acid transmembrane transporter activity	ISO	GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity [inference]

high-affinity basic amino acid transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

high-affinity lysine transmembrane transporter activity

L-arginine transmembrane transporter activity

low-affinity basic amino acid transmembrane transporter activity [inference]

low-affinity L-arginine transmembrane transporter activity

L-amino acid transmembrane transporter activity

L-ornithine transmembrane transporter activity

high-affinity L-ornithine transmembrane transporter activity

L-lysine transmembrane transporter activity

high-affinity lysine transmembrane transporter activity

L-arginine transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity

L-ornithine transmembrane transporter activity

high-affinity L-ornithine transmembrane transporter activity

L-lysine transmembrane transporter activity

high-affinity lysine transmembrane transporter activity

L-arginine transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MIPCRAVLTFTRCLIRRKIVTLDSLEDSKLCRCLTTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATMTAGVISAVMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLCYEQPKYTPEKDILESCTNATSKSESQVTMLQGQGFSLRTLFNPSALPTRQSASLVSFLVGFLAFLIAGLSILTTYGVQAIARLEAWSLALLALFLVLCAAVILTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMVLGFLIYFAYGIRHSLEGNPRDEEEDEDVCPDNVNAAAEEKSAMQANDHHQRNLSLPFILHEKTSEC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites