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Integrin alpha-9

Summary

UniProt ID: B8JK39
Gene Symbol: Itga9
Gene ID: 104099
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0002048
PubChem: B8JK39
Re-Glyco: B8JK39

Annotation

Keyword: Calcium Cell adhesion Disulfide bond Glycoprotein Integrin Metal-binding Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
cell adhesion	ISO	GO_REF
cell adhesion	IEA	GO_REF GO_REF
integrin-mediated signaling pathway	IBA	GO_REF
neutrophil chemotaxis	IGI	PMID
negative regulation of vasoconstriction	ISS	GO_REF

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cellular process [inference]

cell adhesion

cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

neutrophil chemotaxis

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
basal plasma membrane	IDA	PMID
cell surface	IBA	GO_REF
integrin alpha9-beta1 complex	ISO	GO_REF GO_REF
integrin alpha9-beta1 complex	IDA	PMID
integrin alpha9-beta1 complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex [inference]

integrin alpha9-beta1 complex

protein complex involved in cell adhesion [inference]

integrin complex [inference]

integrin alpha9-beta1 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex [inference]

integrin alpha9-beta1 complex

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane region [inference]

basal plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
collagen binding	ISO	GO_REF
collagen binding	IEA	GO_REF
signaling receptor activity	IBA	GO_REF
laminin binding	ISO	GO_REF
laminin binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding [inference]

integrin binding involved in cell-matrix adhesion

laminin binding

cell adhesion molecule binding [inference]

integrin binding [inference]

integrin binding involved in cell-matrix adhesion

cell adhesion mediator activity [inference]

cell-matrix adhesion mediator activity [inference]

integrin binding involved in cell-matrix adhesion

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding [inference]

integrin binding involved in cell-matrix adhesion

collagen binding

extracellular matrix binding [inference]

laminin binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGGPAAARTGAGGLRALLLALVAAGVPAGAYNLDAQRPVRFQGPSGSFFGYAVLEHFHDNTRWVLVGAPKADSKYSTSVKSPGAVFKCRVHTNPDRRCTELDMARGRTRGAPCGKTCRGDRDDEWMGVSLARQPRADGRVLACAHRWKNIYYEADHILPHGFCYLIPSNLQAKGKVLIPCYEEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTLKVLNLTDNTYFKLNDEAIMNRRYTYLGYAVTAGHFSHPSITDVVGGAPQDEGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVGAPMFSEIRDEGQVTVYLNQGHGALEEQLTLTGDAAYNAHFGESIANLGDIDDDGFPDVAVGAPKEEDFAGAVYIYHGDANGIVPKYSMKLSGRRLNPTLRMFGQSISGGIDMDGNGYPDVTIGAFLSDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTVCFRFHGKNVPGEIGLNYNLTADVAQKEKGQLPRVYFVLFGETAGQVSERLQLSHMDEVCHHYVAHVKRRVQDVISPIVFEAAYSLDEHVMGEEDRELPDLTPVLRWKKGQRISQKNQTVFERNCQSEDCAADLQLRGKLLLSSVDEKTPHLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEILSFIVTAQSGNLERSEALHDNTLTLTVPLVHEVDTSITGIVSPTSFVYGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFPSRLSPGGAEMFQVQDMVVSQEKGNCSLQRNPTPCIIPQEQENIFHTIFAFFSKSGRKVLDCEKPGSFCLTLHCNLSALPKEESRTINLYMLLNTEILKKDSSSVIQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDGWDWVQKNQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
226	N-linked (GlcNAc...) asparagine	UniProt
494	N-linked (GlcNAc...) asparagine	UniProt
515	N-linked (GlcNAc...) asparagine	UniProt
613		GlycoProtDB
808	N-linked (GlcNAc...) asparagine	UniProt
855		GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
ECM proteoglycans	Mus musculus
Integrin cell surface interactions	Mus musculus
Signal transduction by L1	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements