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Protein disulfide-isomerase A2

Summary

UniProt ID: D3Z6P0
Gene Symbol: Pdia2 Pdip
Gene ID: 69191
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0002251
Re-Glyco: D3Z6P0

Annotation

Keyword: Alternative splicing Chaperone Disulfide bond Endoplasmic reticulum Glycoprotein Isomerase Redox-active center Reference proteome Repeat Signal Steroid-binding

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	Reference
protein folding	IBA	GO_REF
response to endoplasmic reticulum stress
platelet aggregation	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

protein folding

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

Displaying **all 3** entries
GO Term	Evidence Code	Reference
endoplasmic reticulum
endoplasmic reticulum lumen	ISS	GO_REF
endoplasmic reticulum lumen	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	Reference
protein disulfide isomerase activity	TAS	PMID
protein disulfide isomerase activity	IBA	GO_REF
steroid binding
protein-disulfide reductase activity	ISO	GO_REF
protein-disulfide reductase activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity [inference]

protein-disulfide reductase activity

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, transposing S-S bonds [inference]

protein disulfide isomerase activity

catalytic activity, acting on a protein [inference]

binding [inference]

lipid binding [inference]

steroid binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDKQLLPVLLLLLGVSGSWGQGEEPGGPSEVLPEEPTGEEVPKEDGILVLNHRTLSLALQEHSALMVEFYAPWCGHCKELAPEYSKAAALLAAESAVVTLAKVDGPAEPELTKEFEVVGYPTLKFFQNGNRTNPEEYAGPKTAEGIAEWLRRRVGPSATHLEDEEGVQALMAKWDMVVIGFFQDLQGKDMATFLALAKDALDMTFGFTDQPQLFEKFGLTKDTVVLFKKFDEGRADFPVDKETGLDLGDLSRFLVIHSMHLVTEFNSQTSPKIFAAKILNHLLLFVNQTLAQHRELLTDFREAAPPFRGQVLFVMVDVAADNSHVLNYFGLKAEEAPTLRLINVETTKKYAPTGVIAITAASVAAFCQAVLHGEIKHYLLSQEIPPDWDQGPVKTLVSKNFEQVAFDETKNVFVKFYAPWCSHCKEMAPAWEALAEKYKDREDIVIAELDATANELEAFSVLGYPTLKFFPAGPDRKVIDYKSTRDLETFSKFLDSGGHLPKEEPKEPAASAPEAQANSTLGPKEEL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites