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Angiotensin-converting enzyme

Summary

UniProt ID: E7F9E5
Gene Symbol: ace2 zgc:92514
Gene ID: 492331
Organism: Danio rerio (zebrafish)

External Links

Re-Glyco: E7F9E5

Annotation

Keyword: Carboxypeptidase Cell membrane Cell projection Chloride Cytoplasm Disulfide bond Glycoprotein Metal-binding Metalloprotease Phosphoprotein Reference proteome Secreted Signal Transmembrane helix Zinc

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	Reference
angiotensin maturation	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing [inference]

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
obsolete extracellular space
cytoplasm	IEA	GO_REF
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
cilium	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

Displaying **all 5** entries
GO Term	Evidence Code	Reference
carboxypeptidase activity	ISS	PMID
metallopeptidase activity	IBA	GO_REF
metallopeptidase activity	IEA	GO_REF
peptidyl-dipeptidase activity	IEA	GO_REF
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity

exopeptidase activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MCARWLLLLALASVACCQTVEDRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENADKEAEAYAIWSEYYNKMSEESNAYPIDQISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTATVCKIDDPTDCQTLEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLMIPYPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQKNNRVPGWNVNVNPGVLTSSFINDAEISENAFKVRISLKSALGNEAYTWNANDIYLFKSTMAFAMRQYYLKEKNTDVNFTPENIHTYNETARISFKFAVMDPTKTGTVIPKAEVENAIWQERDRINGAFLLSDETLEFVGLMATLAPPKEEKITIWLVVFGVVMGVTVLAGIYLVTTGILNRKKKAKKAKEASVENPYDGSDDGEVNKAFEEDIEQTGL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
328	N-linked (GlcNAc...) asparagine; partial			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Metabolism of Angiotensinogen to Angiotensins	Danio rerio

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

International Collaboration

Acknowledgements