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Receptor-type tyrosine-protein phosphatase O

Summary

UniProt ID: E9Q612
Gene Symbol: GLEPP1 PTPU2 Ptpn15 Ptpro
Gene ID: 19277
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0002522

GlyConnect

Receptor-type tyrosine-protein phosphatase O

GlyGen

E9Q612

Re-Glyco

E9Q612

Annotation

Keyword: Glycoprotein Phosphoprotein Protein phosphatase Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	Reference
cell morphogenesis	IMP	PMID
monocyte chemotaxis	ISS	GO_REF
monocyte chemotaxis	ISO	GO_REF
monocyte chemotaxis	IEA	GO_REF
regulation of glomerular filtration	IMP	PMID

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

cell differentiation involved in kidney development [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

renal filtration cell differentiation [inference]

podocyte differentiation

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell junction assembly [inference]

cell-cell junction assembly [inference]

filtration diaphragm assembly [inference]

slit diaphragm assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

lamellipodium organization [inference]

lamellipodium assembly

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

filtration diaphragm assembly [inference]

slit diaphragm assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

filtration diaphragm assembly [inference]

slit diaphragm assembly

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

glomerulus development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

cell differentiation involved in kidney development [inference]

epithelial cell differentiation involved in kidney development [inference]

glomerular epithelial cell differentiation [inference]

podocyte differentiation

renal filtration cell differentiation [inference]

podocyte differentiation

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

monocyte chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of multicellular organismal process [inference]

negative regulation of glomerular filtration

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of cellular component organization [inference]

regulation of synapse organization

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of renal system process [inference]

regulation of glomerular filtration

negative regulation of glomerular filtration

negative regulation of multicellular organismal process [inference]

negative regulation of glomerular filtration

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
apical plasma membrane	IDA	PMID
lateral plasma membrane	IDA	PMID
dendritic spine	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

lateral plasma membrane

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	Reference
protein tyrosine phosphatase activity	ISO	GO_REF GO_REF
protein tyrosine phosphatase activity	IDA	PMID PMID
protein tyrosine phosphatase activity	IBA	GO_REF
protein tyrosine phosphatase activity	IEA	GO_REF GO_REF GO_REF GO_REF GO_REF
Wnt-protein binding	IDA	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding [inference]

Wnt-protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGHLPRGTLGGRRLLPLLGLFVLLKIVTTFHVAVQDDNNIVVSLEASDIVSPASVYVVRVAGESKNYFFEFEEFNSTLPPPVVFKATYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKNNWEEPSGSFPEDSFIKPPQDSIGRDRRFHFPEETPETPPSNVSSGSPPSNVSSAWPDPNSTDYESTSQPFWWDSASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQMTLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVSTMVTEVNPNVVVISVLAILSTLLIGLLLVTLVILRKKHLQMARECGAGTFVNFASLEREGKLPYSWRRSVFALLTLLPSCLWTDYLLAFYINPWSKNGLKKRKLTNPVQLDDFDSYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMVSEEEEEDWASRHFRINYADEAQDVMHFNYTAWPDHGVPPANAAESILQFVFTVRQQAAKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWLRKKQQFCISDVIYENVSKS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
75	N-linked (GlcNAc...) asparagine			UniProt GlyGen
154	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
227	N-linked (GlcNAc...) asparagine			UniProt GlyGen
279	N-linked (GlcNAc...) asparagine			UniProt GlyGen
380			G76601MX	GlyGen
471	N-linked (GlcNAc...) asparagine			UniProt GlyGen
500	N-linked (GlcNAc...) asparagine		G02815KT	UniProt GlyGen
554				GlyGen
710	N-linked (GlcNAc...) asparagine			UniProt GlyGen
722		30899004	G80920RR G39188ZX G06110VR	GlyGen GlyConnect